Correlation Analysis Between TCM Syndrome Type And Carotid Atherosclerosis In Elderly Patients With Lipoprotein A

Objective:This study investigates the elderly?greater than or equal to 60 years old?lipoprotein a level and the correlation of carotid artery atherosclerosis,as well as the hypercholesterolemia elderly lipoprotein a higher TCM syndrome type distribution with gender,age,smoking,drinking,merge the correlation factors of disease.For elderly patients with lipoprotein increased a provides an objective basis for TCM syndrome differentiation and treatment of parting lipoprotein a plasma concentration and the relationship between carotid atherosclerosis,timely adjust the plasma concentrations of lipoprotein a,to control the development process of the carotid artery atherosclerosis and the atherosclerotic process in the lower the risk of cardiovascular disease.Method:Collected randomly 162 cases of lipoprotein a>300 mg/L and elderly patients as the case group,162 cases of lipoprotein a ?300 mg/L of the elderly as the control group.The patients are collected from Dongfang Hospital Beijing University of Chinese Medicine outpatient and inpatient.According to the authority of the current generally accepted standard syndromes in"Chinese medicine new medicine clinical research guiding principles?trial?"?2002 edition,zheng xiaoyu?,divided the cases group of lipoprotein a>300 mg/L into five syndrome,including phlegm wet repression,spleen and kidney Yang deficiency,liver and kidney Yin deficiency,Yin deficiency hand,qi and blood stasis type.Lipoprotein a diagnostic criteria and cases include exclusion standard according to the 2007 China's ministry of health work officer prevention research center of the China adult dyslipidemia prevention guide and"Chinese medicine new medicine clinical research guiding principles?trial?"?2002 edition,zheng xiaoyu?as the standard.Collect the basic information of the patients,hpi,past medical history,four diagnostic data,carotid ultrasound,lipoprotein a plasma concentration,etc.All the data above all use SPSS21.0 statistical software for statistical analysis.Results:1.The cases group of lipoprotein a>300 mg/L with a higher,merge hypertension is the most,then followed by diabetes,cerebral infarction,coronary heart disease,among them,the cases of 74 cases of cerebral infarction,control group with 42 cases of cerebral infarction,cases with cerebral infarction was significantly greater than the control group?P<0.05?.Lipoprotein increased the incidence of cerebral infarction in patients with a more lipoprotein a normal high,lipoprotein a heighten can increase the incidence of cerebral infarction.2.Cases with clear smoking patients 68 cases,94 cases of patients with smoking history;The control group,with a record 67 cases of patients with smoking,95 cases of patients with smoking history.Cases with clear drinking history of 37 cases of patients,125 cases of patients with history of drinking;34 patients with the control group,there is a clear history of drinking,128 cases of patients with alcohol.Upon examination,the control group and the case group client smoking history,drinking history was no significant difference?P>0.05?,smoking history,drinking history had no obvious effect on lipoprotein a plasma concentration.3.Cases,162 cases of patients,lipoprotein a most patients in 301-500 mg/L,accounted for 59.9%;In patients>900 mg/L,at least 6.8%.Visible,in elderly patients with lipoprotein a higher mainly mild increased.4.Patients,324 cases of carotid plaques in length distribution trend:the case group>the control group?P<0.05?.Show that as the lipoprotein a higher level,in elderly patients with carotid atherosclerotic carotid plaque largest length increased significantly.5.Cases in the group,carotid artery plaque for flat spot 4 cases,hard spots in 2 cases,145 cases of soft spot.In the control group,7 cases of carotid plaques for flat spot,hard spots,9 cases,127 cases of soft spot.Among them,the incidence of carotid plaques case group is higher than the control group,cases of carotid plaques properties than the control group,group of carotid plaques for soft spot is significantly more than the control group?P<0.05?₆.In 324 cases of elderly subjects,upon examination,lipoprotein a levels and carotid arteI.ry plaque largest length were significantly positive correlation?P<0.05?.7.In elderly patients with lipoprotein a higher TCM syndrome type distribution of the overall trend is:Phlegm turbidity deter a certificate>liver and kidney Yin deficiency syndrome>spleen kidney Yang deficiency of qi and blood stasis syndrome syndrome>Yin deficiency hand.8.Case group 10 cases of patients with unilateral lesions occur in the carotid artery,carotid artery lesions occur on both sides of 147 cases of patients,5 patients with carotid artery without pathological changes.Conclusion:1.Lipoprotein a increased the incidence of cerebral infarction in patients with a more lipoprotein a normal high,lipoprotein a heighten can increase the incidence of cerebral infarction.2.History of smoking,drinking alcohol had no obvious effect on lipoprotein a plasma concentration.3.In elderly patients with lipoprotein a higher mainly mild increased,mainly concentrated in 301?500 mg/L.4.With increased lipoprotein a plasma concentration,in elderly patients with carotid atherosclerotic carotid plaque largest length increased significantly.5.With increased lipoprotein a plasma concentration,aging significantly higher incidence of carotid plaques,the nature of the plaques severity also will increase.6.Lipoprotein a plasma concentrations and carotid artery plaque largest length were significantly positive correlation.7.In elderly patients with lipoprotein a higher,phlegm turbidity deter a card in the most,followed by liver and kidney Yin deficiency syndrome.8.Older lipoprotein a increased a merge patients with carotid atherosclerosis,bilateral lesions significantly more than the unilateral lesion.