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Older Dyslipidemia Syndromes And Carotid Atherosclerosis Correlation Of Preliminary Discussion

Posted on:2014-02-05Degree:MasterType:Thesis
Country:ChinaCandidate:H L ChenFull Text:PDF
GTID:2244330398952704Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective:To investigate the dyslipidemia of TCM syndrome type distribution of old patients, and it’s correlation with age,gender,duration, risk stratification, merger disease, lipid levels,carotid atherosclerosis. To provide an objective basis for carotid atherosclerosis in elderly patients with dyslipidemia and improve the effects of traditional Chinese medicine.Methods:Collected315cases of outpatient and hospitalization randomly in elderly patients with dyslipidemia,according to the authority of the current generally accepted standard syndromes of TCM new drug clinical research guiding principles (try out)(2002,zheng xiaoyu). It divides the dyslipidemia into phlegm turbidity repression,spleen kidney Yang deficiency,liver and kidney Yin deficiency,Yin deficiency and yang excess, qi and blood stasis. Dyslipidemia diagnosis standard according to the2007"standard of Chinese adult dyslipidemia prevention guide". Collect basic data and the four diagnostic information, blood fat index, carotid ultrasound, sort data,fill in the questionnaire,all data is using SPSS20.0statistical software for statistical analysis.Results:In315cases of elderly patients with dyslipidemia, the minimum age is60years old, the maximum is92years old. The shortest duration is1month, the longest is30years. The overall trend:the distribution of TCM syndrome type phlegm wet repression>qi stagnancy and blood stasis syndrome>spleen kidney Yang deficiency type>liver kidney Yin deficiency type>Yin deficiency and yang excess type. The most is high-risk patients, most of merge with hypertension, cerebralinfarction.diabetes,coronary heart disease.Hyper cholesterolemia is132cases,162cases high blood triglycerides, mixed hyper lipidemia is79cases,low high-density lipoprotein hematic disease is154cases.311cases of carotid atherosclerosis, plaque formation is252cases,82cases of carotid stenosis. Various types of traditional Chinese medicine are thickening of the carotid artery intima, liver and kidney Yin deficiency type>spleen kidney Yang deficiency type>phlegm turbidity deter type>Yin deficiency and yang excess type>qi stagnancy and blood stasis syndrome type.In315cases of elderly patients with dyslipidemia, TG and age was significantly negative correlation. There has no significant correlation between blood lipid index and the course of the disease. Maximum lengths of the plaques was significantly positively related with age, and HDL-C was significantly negative correlation.Phlegm turbidity deter maximum lengths of the plaques and HDL-C was significantly negative correlation,and LDL-C was significantly positively related with it.The largest plaque thickness and TC was significantly positively related.The spleen kidney Yang deficiency type maximum plaque thickness and LDL-C was significantly positively related.Liver and kidney Yin deficiency type maximum plaque thickness and TC, LDL-C was significantly positively related. Yin deficiency type hand plaque largest the length and the HDL-C was significant ly negat ive correlation,and LDL-C was significantly positively related with it.TG and qi stagnancy and blood stasis syndrome was significantly positively related to carotid intima thickness, maximum plaque thickness and HDL-C was significantly negative correlation.Conclusion:1In elderly patients with dyslipidemia, liver and kidney Yin deficiency and Yin deficiency yang excess type there were significant differences on age distribution.2In elderly patients with dyslipidemia,TG and age is increased with age. Carotid atherosclerotic plaques is closely related to age,HDL-C. It increased with the age. The lower HDL-C value, the greater the incidence of plaques.3In elderly patients with dyslipidemia phlegm turbidity deter a carotid atherosclerotic plaques and TC, HDL-C, LDL-C are closely related. The prevalence of plaque decreases with increased HDL-C, and increases with increased TC, LDL-C. The spleen kidney Yang deficiency type of carotid atherosclerotic plaques and LDL-C are closely related.The prevalence of plaque increases with increased LDL-C. Liver and kidney Yin deficiency type of carotid atherosclerotic plaques and TC,LDL-C are closely related.The prevalence of piaque increases with increased TC, LDL-C. Yin deficiency yang excess type carotid atherosclerotic plaques is closely related to HDL-C, LDL-C.The prevalence of plaque decreases with increased HDL-C, and increases with increased LDL-C. Atherosclerosis and qi stagnancy and blood stasis syndrome, TG,HDL-C is closely related to its hardening rate decreases with increased HDL-C, and increases with increased TG.
Keywords/Search Tags:Carotid atherosclerosis, Serum lipid abnormality, TCMsyndrome type
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