Comparison Of The Efficacy Of Songling Xuemaikang And Losartan Potassium Tablets In The Treatment Of Grade I Of Liver-yang Hyperactivity

Purpose: Song ling xue mai kang capsules on gan yang shang kang controlled treatments with potassium chloride sand jotham syndrone type primary hypertension ? level 8 weeks after the blood pressure decreased,success rate,dynamic blood pressure drop,high blood pressure,blood pressure symptoms improve the situation of traditional Chinese medicine(TCM),high blood pressure,the frequency of category of "headache" severity "vertigo" to improve the situation,the improvement of syndromes,blood lipid,and observation of the experimental drug safety.Materials and methods: Selected cases from February 1,2016 to June 30,2016 in Liaoning province people's hospital outpatient service in line with the diagnostic criteria of hypertension of primary hypertension grade ?,TCM symptom types as 58 patients with gan yang shang kang type.Aged 18-65 years old.The test will be included in the approach to grouping children by randomized,double-blind,58 patients divided into veins,song ling xue mai kang group 29 cases,potassium chloride sand group of 29 cases.The first two weeks are drug washout period.Since 3 weeks,blood veins were given song ling xue mai kang capsule oral three times three day,while giving potassium chloride sand jotham placebo pills 1 piece,an oral,potassium chloride sand jotham tablet group was given potassium chloride sand jotham piece 1 piece,an oral,while giving song ling xue mai kang capsule placebo pine age 3pills three times a day orally,just for six weeks.Observe two groups of patients' blood pressure decreased,blood pressure before and after the treatment success rate,dynamic blood pressure drop,high blood pressure symptoms improve the situation of traditional Chinese medicine(TCM),high blood pressure,the frequency of category "headache" severity "vertigo" to improve the situation,the improvement of syndromes,blood lipid changes.And by observing the blood routine,routine urine and blood ion,fasting glucose,liver function,renal function,blood uric acid and whether any adverse events such as index to evaluate the safety of song ling xue mai kang capsules loose age clinical medication.Results: 8 weeks after the test results are as follows:(1)the main curative effect: the statistical song ling xue mai kang group with potassium chloride sand jotham seat diastolic blood pressure were lower 5.86 + /-1.274 mm Hg and 5.97 + /-1.523 mm Hg,P = 0.780 >0.05,no statistical significance.Through song ling xue mai kang group with potassium chloride sand jotham seat systolic blood pressure were lower 8.00 + /-1.282 mm Hg and 8.21+ /-1.177 mm Hg,P = 0.525 > 0.05,no statistical significance.(2)Secondary outcome indicators:(1)the statistical song ling xue mai kang groups with potassium chloride sand jotham blood pressure success rate were 82.8%,79.3%,P = 0.843 > 0.05,no statistical significance.(2)the statistical song ling xue mai kang group with potassium chloride sand jotham dynamic systolic blood pressure to reduce 8.66 + 8.66 mm Hg,respectively 8.52 + /-1.703 mm Hg,P = 0.744 > 0.744,no statistical significance.Through song ling xue mai kang group with potassium chloride sand jotham dynamic diastolic blood pressure were lower 6.55+ /-1.352 mm Hg and 6.10 + /-1.423 mm Hg,P = 0.224 > 0.05,no statistical significance.(3)the statistical song ling xue mai kang group with potassium chloride sand jotham improve hypertension related symptoms occur respectively quantitative integral fell by 168,28,P =0.000 < 0.05,there is statistical significance,song ling xue mai kang group is better than that of potassium chloride sand jotham piece.(4)the statistical song ling xue mai kang groups with potassium chloride sand jotham improve "headache" severity in quantitative points in 64,25,P = 0.002 < 0.05,there is statistical significance,song ling xue mai kang group is better than that of potassium chloride sand jotham piece,through song ling xue mai kang pine age group with potassium chloride sand jotham improving its severity "vertigo" quantitative score decreased respectively 44,25,P = 0.003 < 0.05,there is statistical significance,song ling xue mai kang group is better than that of potassium chloride sand jotham pine age group.(5)the statistical song ling xue mai kang group with potassium chloride sand jotham in improving syndromes quantitative score decreases to 65,27,P = 0.000 < 0.05,there is statistical significance,veins,song ling xue mai kang group is better than that of potassium chloride sand jotham piece.(6)through blood kang pine age group of patients with blood lipid levels and potassium chloride sand jotham group of patients with blood lipid levels before and after treatment had no statistical significance(P > 0.05).Safety indicators: 58 patients for blood routine,routine urine,ion,liver function,renal function,blood uric acid,fasting blood sugar and other indicators,various testing indexes without abnormal and aggravating,58 patients had no adverse reactions.Conclusion: The research comes to the following conclusion: 1: Song ling xue mai kang capsule reducing liver yang syndrone type primary hypertension ? level of blood pressure level with potassium chloride sand jotham curative effect.2: Song ling xue mai kang capsule is better in improving symptoms and improving TCM syndrome than that of potassium chloride sand jotham piece.3: Song ling xue mai kang capsule in improving blood lipid,no clear effect.4: song ling xue mai kang capsules subjects in the process of clinical trials for eight weeks without adverse reaction.