The Clinical Analysis Of The Related Factors Of Post Stroke Early Anxiety Disorder

Objective To investigate the related risk factors of post stroke early anxiety disorder and to provide a theoretical basis for clinical intervention.Methods A total of 163 patients with acute stroke within 14 days in Neurology Department of Ningxia People's Hospital from November 2015 to December 2017 were enrolled.All patients were assessed with Hamilton Anxiety Scale,46 patients with HAMA score ?14 were enrolled as post stroke early anxiety disorder group(Post stroke early anxiety disorder,PSEAD group),and 117 patients with HAMA score <14 were assigned to non-anxiety group(non-PSEAD group).Clinical data of all patients were collected,including:gender,age,previous medical history,somatic symptoms,laboratory data and craniocerebral imaging.We utilize NIHSS(National Institutes of Health Stroke Scale),BI(Barthel Index)and PSQI(Pittsburgh Sleep Quality Index)rating scales to evaluate the two groups.To compare the differences of clinical data and scores between two groups and to analyze the related factors of post stroke early anxiety disorder.Results A total of 46 patients among PSEAD group,including 43 cases at sight level,2 cases at moderate level and 1 case with severe anxiety.Single factor analysis showed that no significant difference in age,hypertension,diabetes,urinary frequency,type of stroke,lesion location and lesion side between the two groups(P > 0.05).There was a higher incidence of PSEAD in the two groups compared with women,multiple lesions,and patientswith sweating,and the difference was statistically significant(P < 0.05).The NIHSS scores and PSQI scores in the PSEAD group were higher than those in the non-PSEAD group,and the BI scores in the PSEAD group were lower than those in the non-PSEAD group,and the difference was statistically significant(P < 0.05).The hs-CRP level was higher in the PSEAD group than that in the non-PSEAD group,and the difference was statistically significant(P <0.05).Conclusion 1.Female patients,patients with multiple lesions and sweating are more likely to be developed into PSEAD.2.Patients with severe neurological deficits,poor daily living and poor sleep quality are more likely to be developed into PSEAD.3.The increase of hs-CRP level is related with PSEAD.