| Objective: Cerebral infarction(CI), is caused by many reasons, cranial or intra cranial not one or several blood-vessels in brain tissue lesions caused by focal or extensive hypoxic charge disease, it not only cause symptoms such as hemiplegia, aphasia, but also may cause the patients have great psychological stress reaction, leading to the emotional disorders. The common emotional disorders are Post-stroke anxiety(PSA) and Post-stroke depression(PSD).The anxiety, depression, despair, and lack of pleasure can cause the serious impact on functional recovery, can bring about the cognitive and functional decline, and the increase the burden of family and society, directly affect the prognosis of patients. For the further research of the disease,to find out the hidden information from illnesses,improve the recognition rate and the detection rate, providing timely treatment, improve patient’s mental state, speeding up the patient’s recovery, improving the prognosis and outcome of the disease. Through the investigation and analysis of related factors on anxiety and depression, this study aims to find out risk factors, to provide references basis for early warning and intervention treatment.Methods : By using case-control study, the choice of location in Neurology Department of Baoding No.2 Central Hospital, and research 200 patients with acute cerebral infarction, time selection from Sep. 2012 to June 2014, the requirement is the first time from acute cerebral infarction. We use General condition questionnaire survey in patients with relevant information within 3 days from onset, basic data such as sex, age, culture level, etc; According to the medical history or laboratory data of patients, we find out the vascular risk factors of the patients, including hypertension, diabetes, Hyperlipidemia diseases, etc. Patients with their own feelings, using vents scale as the template, objective and non-directive, evaluate their recent negative life events; then doctor confirm lesion area and lesion side through imaging results and signs. Reference Barthel index used to evaluate the daily life ability of patients, neural function defect scale adopted for evaluating ratings for the patients; assess the patient’s level of social support by using social support rating scale. In the first day of second week, the Hamilton anxiety scale(HAMA) and Hamilton depression scale(HAMD) screening positive cases from the group, using the Chi-square test and t test to compare PSD and non PSD and PSA and non PSA in the relavant factors have significance difference or not. Through Single and multiple logistic regression analysis, thus confirming the independent risk factors and protective factors, inspection level of P<0.05.Results: Among 200 patients, 180 cases were used in the result analysis. There were 102 male patients from 41 to 77 years old, and the average age was 60.51±8.974. There were 78 female patients aged from 41 to 75 years old, and the average age was 61.97±7.892. After contrastive analysis(t=1.123, P =0.263), there was no significant difference for age. There were 70 anxiety patients, 62 depression patients, 39 patients suffering from both anxiety and depression. Morbidity of PSA was 38.89% and that of PSD was 34.44%. Neurologic impairment degree, lesion distribution,he lesion side, Hyperlipid- emia diseases and daily life ability of these five factors,including clinical significance for PSD and PSA.The recent negative life events and social support degree had clinical significance for PSA.Owing to reduce the false negative rate, several variables were screened out among above relevant factors through single-factor dichotomy logistic regression analysis, and binary classification by multiple factors logistic regression analysis to determine the independent risk factors For PSA, risk factors included neurologic impairment degree(OR=2.344, 95%CI 1.436-3.827, P=0.001) and recent negative life events(OR=1.139,95%CI1.054-1.23, P=0.001); protective factor was social support degree(OR=0.941;95%CI 0.908-0.974;P=0.001). For PSD, risk factors included neurologic impairment degree(OR=2.564, 95%CI 1.666-3.948, P=0),protective factors were pathology parts(OR=0.602, 95%CI 0.378-0.958, P=0.032).Conclusion: Neurologic impairment degree is the common risk factor for PSA and PSD.For PSA the risk factor is recent negative life events,social support degree is the protective factor.Protective factors of depression disorder after cerebral infarction is the lesion area. |
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