Clinical Study On The Effect Of Acupuncture On Serum TXA₂ In Patients With Cervical Spondylotic Radicular Disease

ObjectiveCervical spondylosis of nerve root type(CSR)is a kind of disease that is difficult to treat effectively,and it is also one of the common diseases and key research subjects in Acupuncture Department.This experiment is to study by using the ancient Chinese "through the" twelve "thorn" in needling manipulation for CSR source theory and clinical curative effect,at the same time to observe and analyze the serum thromboxane(TXA2)in the mechanisms by which the development of CSR disease;correlation with TXA2 induction to summarize the efficacy in clinical curative effect analysis of the treatment process;and further standardize needling techniques,promote their clinical application.MethodsBy taking the literature in ancient books and discusses the existing theory,the unique role of clinical trials of combination of needling plays in the course of treatment,and the needling method in the treatment of CSR play a role;and to explore the function principle.operation standard needling method and clinical application.60 patients with CSR who met the standard were randomly divided into treatment group,30 cases in the treatment group were treated by the side acupuncture method,and 30 cases in the control group were treated by regular acupuncture.The treatment was once every other day,ten times for a course of treatment.After continuous treatment for two coturses,the serum TXA:concentration,visual analogue scale(VAS)and cervical disability index(NDI)score of the two groups before and after treatment were evaluated.ResultsThe scores of the two group of cases before and after treatment were not statistically significant(P>0.05).so it was comparable.After two cycles of treatment by continuous.VAS score of two groups were significantly lower than before treatment(P<0.05),and the treatment group after treatment.VAS scores were significantly lower than the control group(P<0.05):the two groups after treatment NDI scores were significantly lower than before treatment(P<0.05),and the treatment group after treatment,NDI scores were significantly lower than the control group(P<0.05).The serum TXA2 of the two groups before treatment was higher than that of the healthy adults(P<0.01).The serum TXA2 concentration in the two groups decreased significantly after treatment(P<0.05),and the serum TXA2 concentration in the treatment group was significantly lower than that in the control group(P<0.05).The total effective rate in the treatment group was 93.I%and the control group was 85.2%.The difference was statistically significant(P<0.05).Conclusion①The total effective effect of the two groups after treatment showed that the total effective rate of the treatment group was better than that of the control group,with significant difference(P<0.05);②The concentration of serum TXA:2 in 60 Patients with CSR was higher than that in normal adults(P<0.05);③TXA2 is closely related to the pathogenesis of CSR and the progress of disease.Its mechanism is due to its involvement and aggravation of the contraction of the surrounding vessels,affecting the metabolism of the surrounding tissues and causing the pain to aggravate;④The needling method has a good clinical effect on CSR,and it can relieve pain and delay symptoms.It is worth promoting in order to benefit CSR patients.