Clinical Observation On The Effect Of Ruyi Golden Yellow Powder On The Analgesia Of Knee Osteoarthritis

Objective: Ruyi golden is according to the famous doctor of Ming dynasty,the first hospital in wuhan city Chen Shigong the surgical authentic records of golden adjustment of development,it is a kind of Chinese traditional medicine preparation for external use only,can invigorate the circulation,swelling,heat,pain,etc.,it is very common in clinical application.The clinical observation experiment,ruyi golden powder with diclofenac diethylamine milk gel(lifted him Lin)for parallel comparison,observe whether ruyi golden powder to treat rheumatic fever bi model of knee osteoarthritis,is safe and reliable.Methods: According to the diagnostic criteria of osteoarthritis of knee joint,and referring to the indications and contraindications of golden yellow powder,the case criteria of the test were formulated: inclusion and elimination criteria.In April 2015 to April 2018,three years,in the orthopaedic clinic,the first hospital in wuhan city,including outpatient and hospitalization of patients,select 80 cases of patients with knee osteoarthritis,TCM syndrome type belong to rheumatic fever bi type,and the limit between 62-84-year-old age.Research object ruyi golden yellow,with diclofenac diethylamine gel(lifted him Lin),80 patients were randomly divided into two groups,using belongs to a group of golden powder,use hand he Lin belongs to the control group;The number of patients in the experimental group was 3 times that of the control group,i.e.,ruyi golden powder treatment group: diethylamine diclofenac cream treatment group =3:1.Detailed records of the test and control of patients' basic information and medical history are required to be true and reliable.After the detailed test procedures and requirements are formulated,the patient shall be informed of the situation,and the consent of the patient shall be obtained.Procedures are required throughout the treatment,whether medication,examination,or follow-up,and each step is documented for data reference.The data were statistically compared to verify the safety of experimental drugs in the treatment of knee osteoarthritis(rheumatopharyngeal type).Results: No adverse reactions or adverse events occurred in the trial of ruyi golden powder,and the symptoms and signs of most patients could be improved.It indicates that this medicine has definite therapeutic effect.High security.Summarize the therapeutic effect of two groups,it is concluded that both can't cure the disease,the two groups show the efficiency of the experimental group and control group,42.11%,38.89%,the recovery was 52.63%,55.56%,the efficiency of 5.26% and 5.56%,total effective rate were 94.74%,94.44%,by using the data statistical analysis,found that after treatment system,the experimental knee osteoarthritis patients' clinical symptoms and signs were eased to some extent and improved,by using the data statistical analysis,It was found that the data results between the experimental group and the control group were statistically different(P<0.05)and had clinical significance.After treatment of the experimental group and the control group,by WOMAC and VAS score,compare did state of patients after treatment in patients with joint pain relief,joint activities have improved,rigid degree whether have change,the three aspects of the data collection,found that there are significant differences,shows that the experimental group and the control group has good treatment effect,and the curative effect of two groups.When evaluating the safety and reliability of drugs,no adverse reactions or side effects(related drugs)occurred in the drug group during the whole test,and the incidence rate was 0,with no significant difference.Before and after the treatment,each of our patients with the basic physical examination,eliminate the disease of influential to the test on records and the following several aspects of the inspection,such as electrocardiogram(ecg),see if there is a heart disease;If abnormal blood routine indicates the possibility of infection or severe anemia;If urine fecal routine,recent urinary tract infection or peptic ulcer;To observe the liver and kidney function,whether there is abnormal liver and kidney function on drug absorption and metabolism;Abnormal calcium and phosphorus in electrolytes;The results of the above indicators collected before and after treatment were statistically analyzed,indicating no significant difference(P>0.05)and no significant statistical significance.Conclusion: It can improve symptom and body sign of patients with live and kidney deficiency with deficiency of that liver and kidney,and does not show signs of skin erythema or other skin allergy,and has no obvious adverse reaction,no change in the electrocardiogram on the patient before the treatment,no abnormality is the result of normal electrocardiogram,no abnormality of urine feces,no abnormality of the live and kidney function,the electrolyte fluctuates normally in the normal range,the high safety of the golden dispersion in the clinic,is worth the clinical physician and patient,and can be used for popularization and application.