Four-Marvel Powder Clinical Observation Of Treatment Of Osteoarthritis Of The Knee

Osteoarthritis of the knee (KOA), is a knee degenerationof articular cartilage and subchondral bone sclerosis, as wellas hyperostosis as the main pathological changes of chronicjoint diseases. The main symptoms of knee pain, stiffness, maybe associated with swelling, joint activities owe Lee. Mainlyaffect learning, joint space narrowing or asymmetric,subchondral bone trabecular structural disorder, the jointssurrounding hyperostosis (lip-like change), the kneearticular surface hypertrophy can cause joint varus or valgusdeformity, joint articular cartilage fragments can formintra-articular loose bodies. Osteoarthritis of the knee wasmainly due to a variety of causes degeneration of articularcartilage and bone hyperplasia, popular talk is the aging ofthe knee is a degenerative changes of the knee, it may be calledsenile knee arthritis or degenerative arthritis of the knee.Osteoarthritis of the knee is osteoarthritis in the knee, thegeneralized osteoarthritis also include some other asepticarthritis disorders. The statistics show that ofosteoarthritis patients is three percent of China’s totalpopulation, of which the majority of knee osteoarthritis. Mainly in the area of clinical treatment, oral medication,including anti-inflammatory painkillers (such asnon-steroidal anti-inflammatory drugs, acetaminophen, COX-2inhibitor), cartilage protective agent, even corticosteroids,the treatment for the lifting of the patient’s clinicalsymptoms, especially pain, has a certain effect, but thesedrugs have some side effects, and not effectively change thepathology of the disease progress, the long-term treatment Theeffect has not been affirmed. According to the characteristicsof the incidence of osteoarthritis of the knee, in clinicaldialectical therapy, and achieved good results for aparticular type of card, use of the Four Wonderful scatteredModified treatment hot and humid the Blockage type kneeosteoarthritis, reduce the incidence of adverse reactions, andhave a good long-term results.ObjectiveStatistics on cases of osteoarthritis of the knee in clinicalanalysis, to explore the Four-Marvel Powder efficacy of thetreatment of hot and humid Blockage knee osteoarthritisMethodTo clinical observation collect Wuhan Chinese MedicineHospital the orthopedic outpatient hot and humid Blockage kneeosteoarthritis and patient cases from March2011to May2012,60cases, according to the different treatment, divided intotraditional Chinese medicine group and the control group. Chinesemedicine group of30patients, including9males and21females,dialectical with Four-Marvel Powder treatment;30patients,including10males and20females, celecoxib oral treatment. In both groups at3months follow-up. Bisector rating using a visual analogscale (VAS) and WOMAC quantization table comparing the analgesiceffect and clinical efficacy before and after3months of treatment.ResultTCM group, the control group, after treatment compared with beforetreatment, WOMAC score quantized values decreased score, VASreduction rate comparison，between the two groups in March afterknee function score compared, the difference was statisticallysignificant (P <0.05).1. The TCM group therapy the damp heat Blockage type of kneeosteoarthritis total effective rate was86.67%; the controlgroup, the treatment of the damp heat Blockage type of kneeosteoarthritis total effective rate was76.67%; After Riditanalysis, the TCM group than the control group on the overallefficacy.2. Four-Marvel Powder treatment group (traditional Chinesemedicine group) and plug celecoxib treatment group (controlgroup) integral comparison before treatment and after treatmentfor the improvement of joint pain, stiffness and functionalactivities, the two groups have a significant effect (P<0.05),but no significant difference (P>0.05) in symptom improvementbetween the two groups.3. Traditional medicine group compared with the control group, TCMgroup long-term efficacy and stability, good security.ConclusionThe statistical results showed that the Four-Marvel Powder treatment of damp heat the Blockage type knee osteoarthritissignificantly improve the clinical symptoms, relieve joint pain,improve joint function, reduce the incidence of side effects thancelecoxib (P <0.05). Prove Four-Marvel Powder treatment of dampheat the Blockage type knee osteoarthritis with good results.