| Objective : To study the clinical symptoms,changes in white blood cells and neutrophil counts,syndrome integrals,safety and quality of life of patients with lung and spleen deficiency syndrome after treatment with acupuncture and medicine.To evaluate the clinical efficacy of combined acupuncture and medicine in the treatment of leukopenia with pulmonary and spleen deficiency syndrome after lung cancer chemotherapy,and provide a new treatment for the leukopenia of lung and spleen deficiency syndrome after the treatment of lung cancer with integrated traditional Chinese and Western medicine.Methods:48 patients with lung cancer and lung deficiency syndrome after leukopenia were randomly divided into treatment group and control group.Due to patient compliance and other reasons,42 cases were finally completed,21 cases in the treatment group and the control group.The treatment group received oral treatment with acupuncture plus Li Kejun tablets,and the control group was given oral Li Kejun tablets.Both groups took a course of treatment for 10 consecutive days.Both groups took a course of treatment for 10 consecutive days,evaluated the symptoms before treatment,during and after treatment,changes in white blood cell and neutrophil count,syndrome scores,quality of life and safety changes and statistical analysis by SPSS 21.Results:1.Symptoms and Curative Effects:Comparing the symptomatic effects on the 5th and10 th days after treatment,the results showed that the curative effect of the treatmentgroup was significantly better than that of the control group after treatment,Significantly statistically significant(P<0.05).2.Comparison of laboratory inspection counts:2.1 comparison of white blood cell count: before treatment leukocyte control group and treatment group(P>0.05),no statistical significance,indicating that there was no significant difference between the control group and the treatment group before leukocyte treatment;the two groups of treatment for 5,10 days neutrophil countComparison,the results of the treatment group and the control group had significant statistical significance(P<0.05),indicating that the elevated white blood cell count,the treatment group was better than the control group.2.2 Neutrophil count comparison: Before treatment,the neutrophil count in the control group and treatment group(P>0.05),no statistical significance,that is no difference in neutrophil levels before treatment.The comparison of neutrophil counts between the two groups on the 5th and 10 th days showed significant statistical significance(P<0.01),indicating that the neutrophil count treatment group was superior to the control group before and after treatment.2.3 Platelet count: There was no significant difference between before and after PLT treatment(P>0.05).There was no statistical significance.3.Laboratory efficacy: comparing the efficacy of the laboratory tests between the two groups of patients after treatment,the treatment group of 21 patients,markedly effective in 12 cases,effective in 7 cases,invalid in 2 cases,the total effective rate was 90.48%;after treatment.Among 21 patients in the group,4 were markedly effective,9 were effective,8 were ineffective,and the total effective rate was 61.90%.The effective rate of the treatment group was far higher than that of the control group.4.TCM Symptom Score: TCM Symptoms: Comprehensive observation of TCM symptoms scores can be seen,in addition to low-voiced group,the difference between the treatment group and the control group was not statistically significant(P>0.05);the remaining symptoms of TCM syndrome cough,expectoration,There was a statistically significant difference(P<0.05)between loose stools,poor appetite,fatigue,chest tightness,spontaneous perspiration,shortness of breath,and wheezingbetween the treatment group and the control group.The difference was statistically significant between the treatment group and the control group.In particular,it was found that the symptoms improved significantly after treatment,with significant statistical significance(P<0.01).5.TCM Syndrome Total Score: The TCM syndrome scores of the patients before and after treatment were compared.The difference between the treatment group and the control group before treatment was not statistically significant(P=0.611>0.05).Comparing the total scores of TCM syndrome scores on the 5th and10 th days after treatment,the results were statistically significant(P< 0.05),indicating that the improvement of the syndrome after treatment was significantly better than that of the control group.6.Karnofsky score: The treatment group and the control group can improve the score,but the treatment group was significantly better than the control group(P<0.01).Conclusion:The results of this study show that a combination of acupuncture and medicine in the treatment of lung and spleen deficiency syndrome neutropenia after lung cancer chemotherapy is significantly superior to the oral administration of Licorign in terms of clinical symptoms,white blood cell count,neutrophil count,syndrome scores,Karnofsky score,etc.Patients,with statistical significance,no obvious adverse reactions,indicating that patients with lung and spleen deficiency syndrome after lung cancer chemotherapy,combined with acupuncture has obvious advantages,can improve clinical symptoms,improve quality of life,Effectively treat leukopenia and increase the tolerability of chemotherapy. |
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