| Purpose: This study is the traditional Chinese medicine prescription Liangfu pills for the treatment of chronic non-atrophic gastritis(cold coagulation syndrome)clinical study.Its research belongs to the Chinese medicine internal medicine digestive system disease research field.Through the clinical observation of the treatment of chronic non-atrophic gastritis(cold coagulation stagnation),the clinical curative effect of the combination of Jiafu pills and the application of the drug,so as to provide a safe and effective treatment for clinical treatment TheMethod: Changchun University of Traditional Chinese Medicine Hospital(Jilin Provincial Hospital of liver and spleen and stomach clinic,Western medicine diagnosis of chronic non-atrophic gastritis,Chinese medicine diagnosis of stomach pain(cold coagulation stagnation card)patients with a total of 72,into treatment Group and control group according to the ratio of 1: 1 were randomly divided.The treatment group: Liangbai pills(Gao Liangjiang,Xiang fu,Zhi shi,Bai ji and so on),treatment for 4 weeks;control group: Wenwei Shu capsule,treatment for 4 weeks.By recording the treatment before and after treatment of patients with the main symptoms,secondary symptoms and endoscopy and other improvements.To analyze the safety and efficacy of Liangfu pills in treating chronic non-atrophic gastritis(cold stagnation syndrome).Result: After 4 weeks of treatment,the use of statistical software SPASS19.0 analysis of the two groups before and after treatment of the changes in the indicators,and concluded that:(1)the overall efficacy of the two groups of patients compared: treatment group 36 cases,the total effective rate was97.2%,of which 3 cases of clinical cure,markedly effective in 29 cases,effective in 3 cases,1 case;36cases in the control group,the total effective rate was 72.22%,of which clinical cure in 0 cases,markedly effective in 1 case,effective in 25 cases,10 cases.It was concluded from the rank sum test that the difference between the treatment group and the control group was significant(p <0.05).After treatment,the total score of the two groups of patients compared with the treatment group 36 cases,the symptoms after treatment score 3.062 ± 0.412;36 cases in the control group after treatment symptom score of 10.673 ±0.563.From the t test concluded that the two groups of patients after treatment points were statistically significant(p <0.01).Indicating that the treatment group was superior to the control group in improving the overall clinical efficacy of the syndrome.(2)the two groups of patients after treatment,the main symptoms score: epigastric pain,temperature pain reduction after treatment symptom score,the treatment group was1.061 ± 0.187;control group was 2.222 ± 0.192.Epilepsy pain after treatment symptom score,the treatment group was 0.333 ± 0.187,the control group was 1.831 ± 0.231.From the t test concluded that the two groups of patients after the main symptoms of treatment points were statistically significant(p <0.05).Indicating that the treatment group was superior to the control group in terms of overall clinical efficacy of major symptom improvement.(3)the two groups of patients after treatment of secondary symptoms score comparison: to improve the symptoms of Chinese medicine(two fullness,poor appetite,belching,bowel,pan spit water,loose stools dilute),by t test concluded,The difference between the two groups was statistically significant(p <0.05),and the treatment group was superior to the control group in improving the secondary symptoms.The treatment group and the control group were improved(P> 0.05),the effect was not significant,and no significant difference was found in the two groups.(4)Comparison of gastroscopy after treatment in the two groups: In the treatment group,36 cases of endoscopy grade 0,grade1,grade 2 and grade 3 were 0 cases,6 cases,29 cases and 1 case respectively.Group of 36 cases,endoscopy grade 0,1,2,3,respectively,the number of cases were 0 cases,4 cases,30 cases,2 cases.The difference between the two groups was statistically significant(p> 0.05).(5)the two groups of patients in the course of treatment did not appear any adverse reactions and adverse events.In general,the clinical treatment of chronic non-atrophic gastritis(cold coagulation syndrome)is safe and effective.Conclusion: The data obtained from the above results indicate that none of the patients in the treatment of chronic non-atrophic gastritis(cold coagulation stagnation)did not develop any adverse reactions,demonstrating that the use of this method in clinical practice can improve or eliminate the symptoms of the patient,Improve their quality of life and safety.For the clinical treatment of chronic non-atrophic gastritis patients to provide a more safe and effective treatment. |
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