Analysis Of Clinical Features Of 57 Hyperlipidemia Acute Pancreatitis

Objective: The purpose of this paper is to summarize the clinical features of hyperlipidemic acute pancreatitis and acute biliary pancreatitis,and to improve the diagnosis and treatment of HLAP.Method:the date of 57 patients with HLAP(hyperlipidemia acute pancreatitis),in Lanzhou University First Hospital,from January 2013 to November 2016 were analyzed retrospectively.At the same time,60 cases of patients with acute biliary pancreatitis who were diagnosed as acute gallstone pancreatitis were selected by random sampling.Collected the data of general conditions,laboratory and imaging examinations,severity of disease,concomitant disease,complications,treatment and prognosis.The data were recorded and analyzed by Excel and SPSS21.0 software.Result:(1)The basic situation:The age of HLAP group was significantly lower,while the BMI was higher than that of ABP group,the difference was statistically significant(P<0.05).There was no difference between the length of hospitalization and gender(P>0.05).(2)Hyperlipidemia:The TG and CHOL levels in HLAP group were significantly higher than those in ABP group(P<0.05).High density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(LDH-C)were not statistically significant(P>0.05).(3)Biochemistry index and Routine blood test:HLAP group of AST?ALT?TBIL?ALP?GGT and BUN levels were significantly lower than those of ABP group;while the GLu?CHE?Ca2+ and WBC levels in HLAP group were higher than ABP group,the difference were statistically significant(P<0.05);but there was no difference in the AMY?UAMY?LDH?Crea and NEUT% level between the two groups(P>0.05);(4)Clinical symptom:HLAP group with diabetes,fatty liver patients more than ABP group,but the clinical manifestations of jaundice,fever and pancreatic necrosis and abnormal liver function were less,the difference were statistical significance(P<0.05);(5)The HLAP group showed in patients with SAP was more than ABP group,which was consistent with the MCTSI score,and the operation rate of HLAP group was less than ABP group(P<0.05),while between the two groups in mortality and recurrence rate was no difference.(6)To divided the group HLAP into non severe group and severe group,The GLU level?MCTSI score and BISAP score was significantly higher in the severe group,However,there was no difference between the two groups in the general situation,blood lipids,biochemistry,accompanied by diabetes,fatty liver,treatment effect and so on.Conclusion:(1)most of the patients in group HLAP were young and middle-aged patients,among which there were more male patients;(2)TG significantly increased in HLAP patients,Active lipid-lowering therapy was necessary;(3)The number of patients with diabetes and fatty liver in HLAP group was more;(4)Liver function indexes like ALT?AST?ALP?GGT can assist in the diagnosis of ABP.