| BackgroundGout is a common symptom of kind of disease,metabolic disease in general,not a single disease,with the progress of the course of the disease,but then showed high uric acid hematic disease,arthritis,gout stones and different symptoms such as gout kidney.As the new age,changes in the level of life and improve people's diet,gout has become the people around the world feared on any battlefield,the 2nd metabolic disease in addition to diabetes.In nearly a decade,the number of patients with gout is on a rising trend,the younger age development.Modern medicine etiology,mechanisms of gout,etc.It is not clear,treatment of gout effect a radical cure also there is no obvious effective means.Western medicine is in a variety of effective alleviate symptoms of acute gouty arthritis drugs,but its side effects,adverse reactions,patients more feeling unwell,hard to accept.Chinese traditional medicine prescription,on the other hand,in terms of overall patient's tolerance and regulate qi and blood have their advantages and uphold the traditional Chinese medicine "holistic" and "syndrome differentiation" and the doctor has a set of treatment experience on the treatment,the formulas curative effect is remarkable.This study through test three or four remove bi clear soup treatment of dampness heat bizu the clinical effect of the treatment of acute gouty arthritis,and to assess its adverse reactions and relative to the advantage of western medicine treatment,the treatment of gout for the world provide further thoughts and direction.ObjectiveThis clinical study follow the principles and methods of the DME,conducting clinical randomized controlled trials,on the basis of routine treatment,the control group given oral beauty nimesulide tablets treatment,treatment group simply giving oral Sansiqubi Decoction,after treatment by comparing the patient's pain,swelling,alleviate time,1 week after treatment of pain degree,laboratory inflammation index and TCM syndrome integral,evaluate the clinical curative effect of Sansiqubi Decoction and see Sansiqubi Decoction relative to the advantages and disadvantages of nimesulidedispersible tablet,for the Chinese medicine treatment of gout more in-depth and according to the medical application.MethodsThrough clinical randomized controlled method,the selection of guangzhou university of Chinese medicine orthopedics hospital affiliated tutor patients included in the standard in the outpatient service,from January 2016 to December 2016,patients with onset time should be within 48 hours,its according to random number table method in a ratio of 1:1 was a randomized,enter the data statistics,a total of 70 cases of the outcome,is divided into the control group 35 cases,treatment group 35 cases.The treatment time is 1 week,during the treatment,two groups are a daily basis experimental group in Sansiqubi Decoction,the agent once every day,morning and evening meal points suit;Control group oral nimesulide dispersible tablet,one piece every time,2 times every day.In two groups of patients before and after 1 week treatment to the liver and kidney function,blood c-reactive protein(CRP)and uric acid(UA),patients with symptoms,signs and timely and detailed records.The collected data using SPSS22.0 were analyzed.Result1.There were no differences in the age,sex,duration of disease,degree of pain before treatment,CRP,UA and TCM syndrome integral in the twogroups.There was no significant difference between the two groups(P>0.05).2.Two groups of patients with joint pain,swelling,the difference of the alleviate time was statistically significant(P<0.05),illustrate the effect of two groups of treatment was comparable,the control group in alleviating pain and swelling on faster.3.Two groups of patients in pain score(VAS score),CRP and UA and TCM syndrome integral before and after treatment by contrast,in the group had statistical significance(P<0.05);Pain scores after treatment,the UA group comparison between no statistical significance(P>0.05),CRP,the comparison between the TCM syndrome integral groups was statistically significant(P<0.05).Two groups of patients in pain,TCM syndrome integral,CRP and UA has improved,control group to reduce the CRP is more obvious,experimental group to improve symptoms and signs of traditional Chinese medicine is more outstanding.4.The total effective rate in both groups after treatment were compared,the chi-square test,there is no statistical significance(P>0.05),two groups of clinical curative effect quite test object.ConclusionAfter strict test and statistical analysis,the clinical syndrome differentiation to give oral Sansiqubi Decoction in treatment of acute gouty arthritis,not only can significantly alleviate the degree of joint pain,and can effectively reduce CRP and UA level,improve the patients clinical symptoms and signs of traditional Chinese medicine,quickly relieve patients' pain,the restoration of capacity to labor,life,no obvious adverse reactions in the experiment,also did not see obvious function of liver and kidney damage index,is worthy of clinical doctors application promotion. |
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