Clinical Observation On Treatment Of Chill Stagnant Type Unstable Angina Pectoris Of Coronary Heart Disease By Qufengwenban Decoction

Purpose By observing the clinical curative effect and its effect on the changes of serum markers of vulnerable plaque in patients with unstable angina pectoris,and subsequently evaluating the effect of coronary heart disease on unstable angina pectoris,this paper is aimed at investigating the formation and prevention of vulnerable plaques and providing further theoretical basis and clinical basis of traditional Chinese medicine.Method Seventy-six patients with coronary heart disease and unstable angina were selected and divided into two groups by the method of randomized control.The two groups: the treatment group and the control group each has 38 cases.All the patients were given anti-angina,lipid-lowering and other basic treatment.Besides the basic treatment,the control group is also given by the compound Danshen dripping pills(10 pills/time,3 times/day,oral).However,the treatment group is given by the Qufeng Wenban Decoction in addition to the basic treatment.The Qufeng Wenban Decoction was uniformly fried by the hospital pharmacy.Every medical meal was divided into two bags,with 150 ml each,and was taken by the treatment group thirty minutes after breakfast and dinner with an appropriate temperature.After the treatment of the above 76 patients for 4 weeks,we recorded the frequency,duration,severity,and changes of ECG for each patient.Other symptoms such as tongue and pulse ware also recorded.In addition,other indicator such as(Hs-CRP),plasma homocysteine(Hcy),oxidativelow-density(low-density)Lipoprotein(ox LDL)were tested and recorded.Results(1)The total effective rate(86.84%)in the treatment group was significantly higher than those in the control group(68.42%),the difference was statistically significant(P<0.05);(2)the treatment was effective for both groups(P<0.05),but it is more effective in the treatment group(P<0.05),especially in the symptoms of chest tightness,chest pain,palpitations,and shortness of breath;?Before the treatment,there is no statistic symptoms difference between the two groups(P>0.05).But after treatment,there was a significant improvement(P<0.05).In addition,there was significant difference in improvement between the two groups(P<0.05).(4)There were no significant differences in electrocardiogram between the two groups before the treatment(P >0.05),but the difference is significant after the treatment(P <0.05).In addition,such difference is significant between the two groups(P<0.05).(5)There was no significant difference in blood lipid metabolism between the two groups before and after treatment(P>0.05).There was no significant difference in blood lipid between the two groups before the treatment(P>0.05)and there was no significant difference for the control group between before and after the treatment(P>0.05),but for the treatment group,there was a significant difference between before and after the treatment(P<0.05).(6)Compared with that before the treatment,the levels of hs-CRP were significantly different after the treatment(P<0.05).And there was also a significant difference in the levels of hs-CRP between the two groups after the treatment(P< 0.05).?Before the treatment,the levels of ox-LDL were not significantly different(P>0.05).After treatment,the level of ox-LDL in two groups had significant difference compared with that before the treatment,respectively(P<0.05),and there was significant difference between the two groups after treatment(P <0.05)Before the treatment,the ?levels of HCY were not significantly different(P>0.05).After treatment,the level of HCY in two groups had significant difference compared with that before the treatment,respectively(P<0.05),and there was significant difference between the two groups after treatment(P <0.05).?patients in treatment group had symptoms of tolerable mild abdominal pain.No other serious complications appeared.However,patients in control group became more severe.Conclusion The use of Qufeng Wenban Decoction combining with conventional Dangshen pills and conventional anti-angina treatment can significantly shorten the duration of angina pectoris in patients with unstable angina pectoris of coronary heart disease,alleviate the degree of angina pain and improve the performance of ECG.This treatment can not only significantly improve The total effective rate of treatment,reduce the total score of TCM syndromes,it but also improve the clinical symptoms of patients with Chinese medicine.In addition,Qufeng Fumai Decoction can significantly improve blood.