Prochloraz Synthesis Process Improvement Research

The prochloraz is also called the flapping mildew, fresh Ann c sterilization,sportak, microphones, N- propyl- N- [2-(2 minus 2-3 chlorobenzene oxygen radicals) ethyl]- imidazole- 1- formamide, English name: Prochloraz, is a kind of imidazoles broad-spectrum fungicides, pesticides by inhibiting sterol biosynthesis and play a role. For a variety of crops caused by ascomycetes and imperfect fungi disease has obvious control effect, also can be used with most of the fungicide,pesticide, herbicide, has good control effect. But the mi fresh amine production technology in domestic is mainly in the hands of a few production enterprise, like jiang Su Hui feng le, nanjing Red sun chemical, zhejiang chemical, etc., in a dominant position. In production in this paper, the synthesis process route, further study is mainly studied in etherification reaction and amination reaction in two steps to optimize process conditions and operation steps of research work. Lowered the reaction condition for synthesis of production operations, such as the reaction kettle in pressure, temperature and reaction time, improve the conversion rate of materials;In addition, simplifies the operation steps, the water washing process in the etherification reaction and amination reaction into salt operating the two steps in a big steps to remove the water consumption and material loss and decrease the number of transfer for the material and operating losses. Throughout the operation steps to streamline the process, also reduce the output of sewage by more than 60%,thus greatly reduce the environmental pollution, reduce the processing cost and energy loss, only with this effect is more obvious in process improvement, not only reduces the labor intensity, and reduce the loss of the materials have a substantial reduction in the process of sewage.Improvement of the process, the effect significantly, directly benefit on yield and quality stability, and a large number of reducing sewage and unorganized emissions, increased the recovery and recycling of materials, not only to achieve the environmental protection standard of green production, on-site management were opened and specification, to improve the market competitiveness of products and economic benefit is obvious.