A Correlative Study On The Risk Factors Of Depression In Cancer Patients With Different Types Of Cancer

Purpose: Depression is a serious issue for cancer patients, resulting in impaired quality of life and probably shorter survival. However, the incidence of depression in patients with cancer and the relative factors are not uniformed; the impact on the quality of life of patients is not entirely consistent. The purpose of this study is to investigate the prevalence of depression in cancer patients, the relative factors of depression, and the impact of depression on the quality of life of patients.Method: According to the inclusion criteria and exclusion criteria, we chose 260 cases of cancer patients of Qinghai University Affiliated Hospital treated in November 2014- October 2015. All patients being screened by BDI were divided into two groups, respectively for the depression group and non depression group. Analyze of related influencing factors and the difference of quality of life between the two groups.Results:(1) According to the effective 248 questionnaires: 206(83.06%) patients with depression; 78 cases(31.45%) with mild depression; 27 cases(10.89%) with moderate depression; 101(40.72%) cases with severe depression.(2) Factors like gender, economic status, pain, KPS score, duration of disease, degree of culture were statistically significant for cancer-related depression(P<0.05). The age, location of cancer, and informed or not showed no statistically significant difference(P > 0.05).(3) Cancer depression group and non depression group patients in the function of the quality of life scale for physical, role, cognitive, emotional and social functioning and overall quality of life have a certain difference(P < 0.05); in the terms of symptom scale, fatigue, pain, nausea / vomiting, shortness of breath, diarrhea, insomnia, and economic difficulties exist difference(P < 0.05), in anorexia and constipation did not show significant difference.(4) The depression score in cancer patients was negatively correlated with physical function, role function, emotional function and overall quality of life(P < 0.01); and was positively correlated with pain, nausea / vomiting, shortness of breath, diarrhea, insomnia(P < 0.01).Conclusions: 1.The detection rate of cancer depression was 83.06%, which was consistent with research at home and abroad. 2. In patients with malignant tumor, the incidence of depression with related with gender, economic status, pain, KPS score and the degree of culture. Female, poor economic status, with pain, lower KPS scores and lower level of culture were more prone to depression. 3. Cancer depression group VS non depression group patients: the function of life scale in various fields and overall quality of life was different; in terms of fatigue, pain, nausea / vomiting, shortness of breath, insomnia, diarrhea, economic difficulties were different. 4. The depression in cancer patients was negatively correlated with physical function, role function, emotional function and overall quality of life; and was positively correlated with pain, nausea / vomiting, shortness of breath, diarrhea, and insomnia.