1 BackgroundBronchial asthma (bronchial asthma, BA) referred to asthma, it is due to chronic inflammation of the airways leading to increased airway responsiveness, Diffuse, reversible airway obstruction, causing repeated episodes of wheezing, shortness of breath or chest tightness symptoms, coughing, etc, acute exacerbation of chronic duration and clinical remission, chronic persistent weekly varying frequency and (or) with varying degrees of wheezing, shortness of breath, chest tightness, coughing and other symptoms of asthma can be divided according to clinical manifestations. GINA reports that its ultimate goal is to improve the management of effective control of asthma. Asthma treatment is divided into five ladder, ICS is a classic asthma control medication, the fear of long-term use western medicine can cause adverse drug reactions, it is part of the treatment of patients with poor compliance Clinically, chronic and long-term in duration. TCM treatment of chronic persistent asthma has certain advantages.Tutor based on clinical experience combined with literature studies found that "lung deficiency" may be the key to the pathogenesis of these patients, thus establishing the "kidney yang, warm the lung drink, expectorant asthma" as its basic governing law, and created " Xian Tang Soup "treatment, in order to further the efficacy of Xian Long Soup duration of treatment of chronic asthma for objective evaluation,This paper uses randomized controlled clinical trials, so as to explore the treatment of asthma and chronic treatment of Chinese Medicine of the duration of the method and its impact on the lung deficiency on lung function.2 Clinical StudyObjective:To observe Xian Long Soup Treated kidney deficiency type (partial Yang) chronic bronchial asthma duration of clinical efficacy.Methods:60 patients with persistent chronic bronchial asthma patients met the inclusion criteria, the use of random numbers generated by SPSS 20.0 software divided into observation group and the control group (30 cases). The control group received Seretide (50 μg:250 μg,1 each suction, twice daily) inhalation treatment, observation group Seretide (50 μg:250 μg,1 each suction, twice daily) inhalation therapy and oral medicine Xian Long Soup, were treated for 4 weeks. Determination of symptom scores before and after treatment were compared within the overall effect of the symptomatic group and between groups. Do pulmonary function tests before and after treatment, recording ACT scores between groups within the group, recording the number of acute episodes and reliever medication use, recorded during the observation period to upgrade or downgrade medicine treatment. And the results using SPSS20.0 statistical software for statistical analysis.Results:(1) the observation group total effective Syndrome, the total efficiency of the control group are similar, but the control was significantly better than the control group. (2) The main symptom score in TCM, the observation group and the control group of patients can improve breathing, cough, expectoration, mediastinoscopy stuffiness, throat wheezing symptoms, but the observation group improved patient wheezing, cough, sputum and throat wheeze symptoms more obvious advantages. Secondary symptom score in TCM, can significantly improve the observation group than the control group of patients, waist and knees, Lassitude fatigue symptoms. (3) in terms of lung function, lung function groups PEF (L/s), FEV1% were improved, but the observation group than the control group. (4) in terms of asthma control level, the two groups could improve ACT scores, but the observation group than the control group. (5) in alleviating drug use, study group during the observation period the number of patients using rescue medication use and number of days, the number was less than the control group; upgrade or downgrade in terms of treatment, both groups were not observed in patients during the upgrade and downgrade treatment. (6) the observation group and the control group were not found in the course of treatment adverse drug reactions.Conclusion:Xian Long Soup joint Seretide Seretide than the simple use of more effective control of asthma and improve lung function and improve clinical symptoms, particularly wheezing, cough, expectoration, mediastinoscopy stuffiness, waist and knees, Lassitude fatigue symptoms. So Long Sin Treated kidney deficiency type (partial Yang) bronchial asthma have better efficacy and drug safety. |