Study On The Relationship Between Obesity, Diabetes, Hyperlipidemia And Acute Pancreatitis

Purpose:Study on the correlation between hyperlipidemia, obesity, diabetes and acute pancreatitis. Assessment of the impact of the severity and prognosis of acute pancreatitis severity. For the early clinical assessment of severity and prognosis of acute pancreatitis and provide a theoretical basis for. In order to guide the early diagnosis and treatment in severe acute pancreatitis.Method:Analysis of Dezhou Hospital of Traditional Chinese Medicine of Shandong province from January 2001 to December 2015 were 171 cases of acute pancreatitis cases. Classification according to the severity of the disease, According to the acute pancreatitis severity score standard, for example:CT severity index score, CT Balthazar rating, Ranson score, and other standards. Patients were divided into 2 groups, including 33 cases of severe acute pancreatitis and 138 cases of mild acute pancreatitis.On the basis of syndrome diagnostic criteria for metabolic syndrome, Patients were divided into 28 cases of metabolic syndrome and 143 cases of non metabolic syndrome group. A detailed record of patients with gender, age, calculating the body mass indexaccording to body weight (kg)/height (m) 2. Within 24 hours after admission, blood routine examination in patients with fasting CRP levels, blood biochemical index, blood amylase, etc.check routine abdominal ultrasound, CT imaging study. According to the severity of the disease to take comprehensive treatment measures,Observe the changes of clinical index and the time of remission, the occurrence of complications and prognosis of the patients,Comparison of clinical manifestations of severe acute pancreatitis with mild pancreatitis, Correlation analysis of blood glucose and blood lipid, body mass index and severity in acute pancreatitisResult:â‘ Severe acute pancreatitis group and mild acute pancreatitis group: a.The severe acute pancreatitis patients with elderly people. The level of blood glucose, triglyceride and body mass index were significantly increased in patients with severe acute pancreatitis (P<0.05). The difference has statistical significance The proportion of male and female in the two groups was equal,Blood cholesterol levels in the two groups were not different (P>0.05),there was no significant difference, b.Severe acute pancreatitis patients with high-risk obesity. And the number and appearance of fatty liver and diabetes complications was significantly increased in the group. Compared with the mild acute pancreatitis group, the difference has statistical significance (P<0.05)c.The severe acute pancreatitis patients with damage of hepatic function, renal function damage. Compared with mild pancreatitis patients, the difference has statistical significance (P<0.05).â‘¡Acute pancreatitis complicated with metabolic syndrome patients, the basic abdominal pain relief time, average fasting time, average hospitalization days was significantly prolonged, the level of CRP increased obviously, serum calcium levels decreased,local and systemic complications, recurrence rate, mortality rate, significantly increased the occurrence during hospitalization. Compared with no metabolic syndrome in patients with acute pancreatitis, the differences between the two groups were obvious, with statistical significance (P<0.05).â‘¢The blood glucose level, triglyceride level, body mass index (kg/M) was significantly correlated with the severity of the disease index of acute pancreatitis. Blood glucose level, serum triglyceride level, body mass index (BMI, kg/square meters) index were with acute pancreatitis scoring standard of Balthazar CT grading, CTSI score, Ranson score of regression analysis,that showed significant positive correlation (P<0.01).Conclusion:There is a close relationship between blood glucose, triglyceride level, body weight index and the severity of acute pancreatitis. Can be used as an important reference index to evaluate the severity and prognosis of acute pancreatitis. Positive control of body weight, blood glucose and serum lipid in control, can prevent the occurrence and the disease progression of acute pancreatitis.