| Objective:By analyzing the correlation between blood glucose and glycosylated hemoglobin(Glycated Hemoglobin A1 c,Hb A1c)and blood pressure,body mass index(BMI),waist circumference,and blood lipid indicators in the pre-diabetic population in the National Fitness Monitoring Project of the Nanning Sports Bureau.To explore the influencing factors related to pre-diabetes and the occurrence and progression of diabetes.Method:1.The survey subjects were from the people aged 45-74 in the Nanning National Fitness Monitoring Project from 2018 to 2019.All of them signed an informed consent form and performed physical examinations(blood pressure,height,weight,waist circumference)and blood biochemistry(blood sugar,Hb A1 c,Blood lipids)of the survey subjects detection.According to the entry criteria,three groups of normal blood sugar group,pre-diabetes group,and diabetes group were included.90,90,and 110 cases were randomly selected from the total population of each group,and a total of 290 cases were included in the study subjects.2.Adopt a unified standard format to record the general information,physical examination and laboratory test indicators of all groups of research objects.Use SPSS23.0 software for statistical description,compare the clinical characteristics of the normal blood sugar group,pre-diabetes group,and diabetes group,analyze the correlation between glucose metabolism indicators and research factors in the three groups,and calculate and discuss the pre-diabetes and diabetes prevalence Risk factors and independent risk factors.Inspection level: P<0.05Result:1.Compared with people with normal blood sugar,people with prediabetes have higher blood pressure,postprandial blood sugar,and Hb A1 c levels.Diabetics have higher blood pressure,waist circumference,total cholesterol,triglycerides,blood sugar and Hb A1 c levels,and lower high-density lipoprotein levels.With statistical significance(P<0.05);gender,age and BMI levels were not significantly different in normal blood sugar,prediabetes and diabetes(P>0.05).2.The results of Spearman correlation analysis showed that pre-diabetes blood glucose and Hb A1 c levels were positively correlated with blood pressure,BMI,waist circumference,total cholesterol,and triglyceride levels(P<0.05).Diabetic blood glucose and Hb A1 c levels were positively correlated with blood pressure,BMI,waist circumference,total cholesterol,Triglycerides and lowdensity lipoprotein levels(P<0.05),and they were all negatively correlated with high-density lipoprotein levels(P<0.05).3.Single factor logistic regression analysis found that hypertension,high cholesterol,high triglycerides and low high-density lipoprotein are related to prediabetes disease(P<0.05);hypertension,central obesity,high cholesterol,high triglycerides Ester and low-density lipoprotein are related to diabetes mellitus(P<0.05).4.Multivariate logistic regression analysis found that hypertension(O R=4.24,95%C1,1.73-10.38;P=0.002)and high cholesterol(OR=3.32,95%CI,1.33-8.08;P=0.008)are diabetes Independent risk factors in the early stag e;hypertension(OR=8.97,95%CI,3.77-21.32;P=0.000),central obesity(OR=2.24,95%CI,1.11-4.53;P=0.024)are independent of diabetes Risk factors.Conclusion:1.Blood pressure,BMI,waist circumference and blood lipids are correlated with prediabetes,diabetic blood sugar and Hb A1 c.It is suggested that in clinical practice,blood pressure,BMI and other physical monitoring should be carried out for people with impaired glucose metabolism,and the control of blood sugar and blood lipids should be strengthened.2.Hypertension and high cholesterol are independent risk factors leading to the occurrence of pre-diabetes,suggesting that the comprehensive prevention and treatment of hypertension,dyslipidemia and pre-diabetes should be further strengthened to effectively reduce the occurrence and development of prediabetes.3.Hypertension and central obesity are significant independent risk factors for the occurrence of diabetes,suggesting that in the evaluation of obese persons in this region,in addition to BMI and other indexes,we should also focus on indicators such as abdominal circumference to evaluate central obesity.For abdominal obesity Those who should strengthen the theoretical guidance of health education,formulate scientific diet and exercise habits,and carry out individualized intervention are the key strategies for the early prevention of diabetes. |
PDF Full Text Request