The Clinical Research On The Jia Jian Qian Gen San In Treating The Patients Of Qi And Yin Type Two Virtual IgAN Bloody Urine

Objective: this subject aims to observe mentor since plans to add and subtract madder root powder in the treatment of qi and Yin type two virtual IgA nephropathy blood in the urine of clinical observation, to investigate and subtract madder root powder of qi and Yin deficiency type of IgA nephropathy patients urine red blood cell count, 24 hours urinary protein quantitative, renal function, serum creatinine and urea nitrogen) laboratory indexes such as level and the influence of Chinese medicine symptom integral, for the clinical treatment of IgA nephropathy screening efficiency and safety of drugs to provide reliable basis.Methods: according to the cases included in the standard selection of 40 patients with IgA nephropathy, 20 cases were randomly divided into control group 20 cases, and test group. Control group 20 cases: simple hematuria or 24 h urine protein quantitative lg person with tripterygium wilfordii glycoside LMG/more or less(kg. D) + persantin treatment(solution) l; Lg < 24 h urine protein quantitative 2 g or less person with plan 1 plus ARB oral(scheme 2); Experimental group 20 cases, on the basis of control group therapy to give oral Chinese medicine granule preparation daily 1 agent, two groups of treatment for 8 weeks. Observe two groups before and after the treatment of urinary red blood cell count, 24 hours urinary protein quantitative and renal function(serum creatinine and urea nitrogen) laboratory indexes such as level and TCM symptoms the change of the total score, curative effect evaluation.Results:(1) experimental group and control group in clinical curative effect of total effective rate comparison, there were significant differences(P < 0.05).(2) of urinary red blood cell count and the 24 h urine protein quantitative results Two groups before and after the treatment are obvious curative effect(P < 0.05), compared the experimental group significantly after treatment in control group(P < 0.01);(3) effect on renal function in the two groups after treatment serum creatinine and urea nitrogen values have no obvious improvement than before treatment(P > 0.05); Patients serum creatinine than control group obviously improved after treatment(P < 0.05); Urea nitrogen treatment after experimental values than the control group no significant improvement(P > 0.05).(4) influence on TCM syndrome score in the two groups after treatment of TCM syndrome score is obviously improved compared to that before treatment(P < 0.01); Treatment group after treatment of TCM syndrome score is better than that of control group(P < 0.05), the test group was better than control group in improving clinical symptoms of traditional Chinese medicine. In add and subtract madder root powder in the treatment of qi and Yin type two virtual Ig A nephropathy hematuria has obvious clinical efficacy.Conclusion: the treatment group can reduce qi and Yin deficiency type of IgA nephropathy patients with hematuria and proteinuria, helps to relieve the clinical symptoms, protect kidney function and delay the progression, improve patient survival and quality of life, and no toxic side effects, instructions according to the concept and principles of syndrome differentiation and treatment of prescription of add and subtract madder root powder on the treatment of qi and Yin deficiency type of IgA nephropathy hematuria has obvious clinical effect, provides different options for the treatment of the disease.