Clinical Observation Of Chronic Icteric Viral Hepatitis BDamp-heat Syndrome Treated By Qingrejiedu,lishituihuang

ObjectiveThis observation aims to observe the western medicine treatment combined use of traditional medicine dialectical treatment to treat jaundice of damp heat syndrome caused by chronic viral hepatitis b,and compare the clinical efficacy and safety. MethodThis study would be consistent with the standard 5.2014-12.2014 Hubei Provincial Traditional Chinese Medical Hospital outpatient with 40 cases of patients standard in chronological order of treatment were randomly assigned to a treatment group and a control group, each group of 20. Control group was used the basic clinical support therapy combined with rhubarb total anthraquinone capsule(0.25 g, containing rhubarb total anthraquinone 25mg), two at a time, three times a day. Treatment group was used the basic clinical support therapy combined with the dialectical prescription Jingsanhuang Decoction. Continuous administration 4 weeks, observe and record the results. The project mainly includes the main symptoms and physical signs before and after treatment and the numerical of bilirubin(TBIL, DBIL) and the main indicators of liver function(ALT, AST, GGT, ALP). Observe the patient’s vital signs, renal function, blood routine, urine routine, stool routine, and adverse drug reactions, etc., to evaluate the clinical efficacy and safety of the treatment.Data were analyzed by SPSS19.0 statistical software. Count data using chi-square test, measurement data using t test, grade adopts Ridit test. difference was statistically significant in P<0.05. ResultsTreatment group’s TCM symptoms total score compared with control group before and after treatment, the difference is statistically significant. Treatment group’s TCM symptoms total score was lower than the control group, the difference is statistically significant. Some symptoms(jaundice, fatigue, skin itching) on the improvement of the treatment group is better than that of control group. indicating the improvement of the overall symptoms of traditional Chinese medicine, two groups of certain curative effect can be obtained, and the treatment group is better than the control group.Treatment group’s liver function indicators compared with control group before and after treatment, the difference is statistically significant. Some indicators(GGT, TBIL, DBIL) on the improvement of the treatment group is better than that of control group. And the western medicine curative effect evaluation of treatment group effective rate was 85%, slightly higher than the control group 70%, on the improvement of the liver function index, two groups of certain curative effect can be obtained, and the treatment group is better than the control group.Observe two groups of patients, no serious adverse events occurred in the process before and after treatment, The patient’s normal vital signs, blood routine, urine routine and renal function monitoring had no obvious abnormalities. ConclusionResearch results show that: for the treatment of CHB jaundice damp heat syndrome, whether western medicine basic support therapy, or combined dialectical medicine comprehensive treatment, to the improvement of the TCM symptoms, jaundice index, the recovery of liver function index can obtain satisfactory curative effect. Among them for some symptoms(jaundice, fatigue, skin itching) and indicators(GGT, TBIL, DBIL) on the improvement of the treatment group is better than that of control group, suggests that traditional medicine dialectical treats for jaundice on the improvement in symptoms subsided and cholestasis conditions there is a certain advantage. During the treatment, two groups had no adverse events occur, normal vital signs before and after the treatment, indicating that the Jingsanhuang Decoction treatment for CHB jaundice damp-heat syndrome has a curative effect affirmation, less adverse reactions, worthy of clinical popularization and application.