| Purpose:By observing the effect of Lidan Tuihuang Decoction on obstructive jaundice(liver and gallbladder damp-heat syndrome)LC+LCBDE postoperative liver function recovery,TCM symptom score,patient jaundice resolution time and hospital stay,to explore the effect of Lidan Tuihuang Decoction on obstructive jaundice LC+LCBDE operation Promote the clinical curative effect of reducing yellow and improving liver function.Material and method:From December 2018 to September 2020,inpatients in the Department of Integrated Traditional Chinese and Western Medicine Surgery in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were collected.Western medicine diagnosed common bile duct stones and obstructive jaundice,and Chinese medicine diagnosed jaundice.The syndrome is liver and gallbladder damp-heat.There are a total of 63 cases in this trial.During the trial,there were 1 case in the control group and 2 patients in the traditional Chinese medicine group who dropped out due to unfinished trials.A total of 60 cases were actually completed in the clinical trial,30 cases in the control group and 30 cases in the traditional Chinese medicine group.All patients underwent LC+LCBDE combined with T-tube drainage.After the operation,patients who received conventional Western medicine anti-infection combined with liver protection were included in the control group;the traditional Chinese medicine group took Lidan Tuihuang Decoction 100ml on the first day after the operation on the basis of Western medicine conventional treatment.2 times/d,the course of treatment is 2 weeks,observe the clinical efficacy.Record the ALT,AST,TBIL,DBIL values of the 2 groups before and on the 3rd,5th,8th,and 14th days after the operation,as well as the TCM symptom score,jaundice resolution time and hospital stay,and SPSS26.0 software was used for statistics analysis.Results:1.Liver function indicators:①On the 3rd day after operation,there was no significant difference in TBIL,DBIL,AST,ALT between the two groups(P>0.05);②On the 5th day after operation,there was a significant difference in DBIL,ALT between the TCM group and the control group.Significance(P<0.01),there was no statistically significant difference in TBIL and AST indexes(P>0.05);③Comparison of TBIL,DBIL,AST,ALT between the two groups on the 8th and 14th day after surgery,the difference was statistically significant(P<0.05).2.TCM syndrome scores:There are differences in the scores of the two groups after the operation compared with the scores before the operation,and the difference is statistically significant(P<0.01).(1)Dry mouth and throat score:①On the 3rd day after operation,the difference between the TCM group and the control group was not statistically significant(P>0.05);②On the 8th day after the operation,the difference between the TCM group and the control group was statistically significant(P<0.05);③On the 14th day after operation,the difference between the traditional Chinese medicine group and the control group was statistically significant(P<0.01).(2)Nausea and vomiting score:①The score of the traditional Chinese medicine group was significantly lower than that of the control group on the 3rd day after the operation,and the difference was statistically significant(P<0.05);②The control group and the traditional Chinese medicine group were on the 8th day after the operation and the first day after the operation,respectively.On the 14th day,the score decreased,and the difference was statistically significant compared with that before operation(P<0.01).(3)Tongue coating score:①There was no statistically significant difference between the TCM group and the control group on the 3rd postoperative day(P>0.05);②The TCM group was significantly different from the control group on the 8th and 14th day after the operation.(P<0.01).3.Total effective rate:On the 14th day after operation,the total effective rate of TCM in the control group was 80.00%and that in the TCM group was 96.67%.The difference between the two groups was statistically significant(P<0.05).4.Jaundice resolution time and hospital stay:the TCM group was less than the control group,the difference was statistically significant(P<0.01).Conclusion:Lidan Tuihuang Decoction for patients with common bile duct stones,obstructive jaundice(liver and gallbladder damp-heat syndrome)undergoing LC+LCBDE surgery can reduce jaundice,promote the recovery of liver function(TBIL,DBIL,AST,ALT),and improve TCM symptoms(distressed mouth and throat).Dryness,nausea,vomiting,tongue coating),improving the total effective rate,shortening the time of jaundice and hospitalization,have obvious advantages compared with the conventional treatment of western medicine. |
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