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Correlation Of EB Virus And Mycoplasma Pneumonia And T Lymphocyte Subsets In The Children With Acute Laryngitis

Posted on:2016-09-18Degree:MasterType:Thesis
Country:ChinaCandidate:L P LiFull Text:PDF
GTID:2284330467998960Subject:Otorhinolaryngology
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Because of environmental governance lags behind economicdevelopment, increased pollution, combined with the domestic abuse ofantibiotics, resulting in children with acute laryngitis incidence rateremained at a high level. Infants with respiratory rich in blood vesselshave, pharynx narrow characteristics. Easily cause infection after acutelaryngitis pharyngeal mucosa congestion, respiratory tract edema. Easilylead to laryngeal obstruction, severe and even life-threatening.Purpose:By some children admitted to hospital for statistical analysis, tounderstand the cause of children with acute laryngitis, Correlationbetween lymphocyte subsets, CRP and WBC changes in children withacute laryngitis, prevention and treatment of children with acute laryngitisis provided theory.Methods:In strict accordance with the inclusion criteria,361cases of childrengather in January2014–December2014to come to our hospital, where:the case group307cases,54cases in the control group. Gender case andcontrol groups were recorded on the patient group recorded cases oflaryngeal obstruction, using PCR methods to collect patient group MP,EB virus infection, the use of C-reactive protein blood analyzer casegroup and the control group CRP levels using five categories of blood analyzer case group and the control group WBC levels, using microarraytechnology to detect cell-mediated immunity in case group and thecontrol group T lymphocyte subsets. According to whether childreninfected children with acute laryngitis MP, EB virus infection turn intothe case group and uninfected group. Establish a database using SPSS17.0, and the data were analyzed: gender analysis using χ2test; fornormally distributed data discrepancies rank sum test.Result:1. The case group and the control group sex (χ2=8.406, P=0.004),a statistically significant difference. The results show that: the existenceof gender differences in children with acute laryngitis. Age groupcomparison shows that the most acute laryngitis disease cases in group1year, followed by6months~1year old group, group again for2yearsold, after3years old group, February to may, the rest are relatively rareamong all age groups.2. The difference between T lymphocyte subsets EB virus infectionand uninfected both rank test results showed that infection and uninfectedgroup, T lymphocyte subsets differences were not statistically significant.For differences in CRP, WBC between EB virus infection and uninfectedboth rank test results showed: and infection uninfected group, thedifference was not statistically significant. Description EB virus infectionin children with acute laryngitis T lymphocyte subsets in children, CRP,WBC no effect.On the difference between T lymphocyte subsets MP infection anduninfected both rank test results showed that: infection and uninfectedgroups was not statistically significant. For differences in CRP, WBCbetween MP infection and uninfected both rank test results showed: infection uninfected group, the difference was not statistically significant.Description MP infection in children with pediatric acute laryngitis Tlymphocyte subsets, CRP, WBC no effect.3. For the case group and the control group T lymphocytes rank sumtest, the results showed that: CD8+T lymphocytes were significantlydifferent patient group and the control group(Z=-2.835,P<0.05), CD4+, CD3+, CD4+/CD8+no statistical difference. Description suppressor Tlymphocytes in children with acute laryngitis and relevant.4. For the case group and the control group CRP, WBC rank testresults showed: CRP (Z=-4.697, P<0.05), WBC (Z=-2.904, P<0.05),the case group and the control group were significantly different,indicating that children Acute laryngitis and CRP, a correlation betweenWBC.5. Children with different degrees of laryngeal obstruction of Tlymphocyte count, CRP, WBC rank test results showed that: varyingdegrees of throat obstruction in children between CD4+/CD8+(χ2=8.896, P<0.05), CRP (χ2=8.370, P<0.05)has a statistically significantdifference, indicating varying degrees of laryngeal obstruction betweenT-lymphocyte subsets, CRP and relevant.In summary, the existence of gender differences in children with acutelaryngitis, and nothing to do with changes in T lymphocytes EB virus,MP infection. The statistical analysis showed that there is a differencebetween the normal population of CD8+T lymphocytes, CRP, WBC and.Not only that, concurrent with varying degrees of laryngeal obstructionCD4+/CD8+, there is a correlation between the CRP. Therefore, in theprevention and treatment of children with acute laryngitis, should focus on observation of CD8+T lymphocytes, CD4+/CD8+, CRP, WBC’schanges.
Keywords/Search Tags:acute laryngitis, T lymphocytes, CRP, WBC, laryngeal obstruction
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