Analysis Of Knee Osteoarthritis Treatment Of Intra-articular Injection Of Sodium Hyaluronate Different Radiological Characteristics

Outpatient collect knee osteoarthritis, according to the imaging features are grouped grouped receiving sodium hyaluronate(Si Peite) a course of treatment, pre-treatment and post-treatment knee WOMAC score improvement rate was calculated for each group clinical efficacy understand different characteristics of sodium hyaluronate images in patients with osteoarthritis of the knee and analyze its causes, to guide clinical knee osteoarthritis treatment period, increase sodium hyaluronate treatment of knee osteoarthritis.Methods: Collection of knee osteoarthritis patients, the inclusion criteria were selected patients with osteoarthritis of the knee and received intra-articular injection of sodium hyaluronate treatment of 113 patients with knee osteoarthritis, shooting after double knee radiographs according to its image Characteristics divided into articular cartilage hardening bone formation associated with tibial spine tapering group(A), the formation of osteophytes(group B), joint space narrowing(group C).Fill out personal information and knee grouping WOMAC score, and then take a course of intra-articular injection of sodium hyaluronate treatment, the first month, the first six months of follow-up after treatment was given another knee WOMAC score before treatment and after treatment calculation The score difference obtained sodium hyaluronate treatment improvement rate in each group. The joint clinical trials using WOMAC function score, score difference between the percentage score ratio before treatment before treatment and after treatment is the joint between the functional improvement rate(RIS), RIS> 25% is therapeutically effective, RIS ≤ 25% for the treatment ineffective. Characteristics of knee pain was observed different characteristics of the image corresponding to knee osteoarthritis patients and other clinical signs, the image corresponding to the different characteristics of knee osteoarthritis patients receiving sodium hyaluronate treatment of clinical improvement rate statistics Learn compare and analyze their causes.Result: Included in the experiment of 113 cases of patients with osteoarthritis of the knee pain, knee pain following characteristics floor squat pain mainly pain and other pain can also occur upstairs, stand the pain and go flat pain, pain down the stairs, squatting pain, pain, go upstairs, go stand pain and pain incidence plains were 90.2%, 87.6%, 81.4%, 78.9%, 39.8%. Pain and squat down high pain occur more pain characteristics.Radiological properties of articular bone sclerosis 80.7% effective rate in group A after intra-articular injection of sodium hyaluronate with tibial spine between the tapering end of a course of formation of the first month, the first six months of the effective rate of 84.6%; group B intra-articular injection of sodium hyaluronate radiological characteristics of the formation of osteophytes treatment after a first month of the effective rate of 60.0%, the effective rate was 80.0% in the first six months; and radiological characteristics of the joint space change injection of sodium hyaluronate narrow group C articular treatment after a first month of the effective rate of 54.1%, the effective rate was 27.0% in the first six months. Group A and Group B joint symptoms improved treatment efficiency rate that is increased with sodium hyaluronate treatment after treatment time gradually increased, group C joint improvement rate that is increasing the efficiency of treatment with sodium hyaluronate after the end of treatment course of time gradually reduced. Intra-articular injection of sodium hyaluronate treatment of knee osteoarthritis overall treatment after the first six months of the effective rate of 63.7%. After basis between radiographic features grouped by X2 test group treatment, X2 = 32.191, P <0.005, in the first six months after the treatment difference between groups was statistically significant.A group after the intra-articular injection of sodium hyaluronate course of the first month of the effective rate of 80.7%. After the treatment, the effective rate of the first six months was 84.6%, by X2 test(fourfold table) Comparison of January and the first 6 months after treatment according to the patient radiological characteristics of sodium hyaluronate grouping A group therapy, X2 = 5.778, P <0.05, differences between the first of January and the first six months of treatment effect of sodium hyaluronate in group A after treatment was statistically significant. Group B intra-articular injection of sodium glass after the first month of treatment response rate was 60.0%, the first six-month rate was 80.0% for treatment of patients grouped according to the radiological properties of group B by X2 test(fourfold table) The first in January compared with the first six months after treatment, X2 = 4.762, P <0.05, the first in January and the first difference six months of treatment effect of sodium hyaluronate in group B after treatment was statistically significant. Group C intra-articular injections of sodium treatment after the first month of the effective rate of 54.1%, the first six months was 27.0 percent effective for treatment of patients grouped according to the radiological characteristics of the group C by X2 test(fourfold table) After January compared with the treatment of the first six months, X2 = 5.606, P <0.025, Differences between January and the first six months of treatment effect of sodium hyaluronate in group C after treatment was statistically significant.Inconclusion: 1, the imaging characteristics of the formation of subchondral bone sclerosis group B patients with tibial eminence sharpened A group representing patients and osteophyte formation imaging characteristics of the group C patient a therapeutically effective joint space narrowing rate.2, the imaging characteristics of the formation of subchondral bone sclerosis A with tibial spine between the tapering and osteophyte formation, joint symptoms improved rate of group B patients with increasing sodium hyaluronate after the end of treatment course of time and gradually increase; Imaging patients characterized by narrowing of the joint space group C with increasing efficiency of sodium hyaluronate after the end of treatment course time and gradually reduced.