The Clinical Observation Of Juan Bi Particles In The Treatment Of Knee Osteoarthritis On Hanshi Bizu Syndrome

Objective:To observe the validation Juan oral on knee osteoarthritis and dampness bizu bi particles on the improvement of their clinical symptoms and signs of the medical experience, on the basis of the theory of fu Yang, with cold dampness treatment knee osteoarthritis, comprehensive evaluation Juan bi particles in the treatment of knee osteoarthritis clinical efficacy and safety of Juan bi particles treat type cold dampness bizu provides the theory basis for knee osteoarthritis.Methods: According to the inclusion criteria to choose cases 72 cases, randomly divided into two groups, observation group 36 cases, to Juan bi particles 15 g, Po, dar. Control group to the laurel bone pain particles 5 mg, Po, dar. The two groups in January for a period of treatment. Observed two groups of patients before and after treatment the total curative effect, clinical symptoms and physical signs, X-ray and other indicators, with reference to the clinical research of new drug of TCM principles related content as the main basis set standard comparison, curative effect evaluation.Results: Plan to investigate 60 cases, actual survey 72 cases, including unfinished treatment falls off in 4 cases, the audit does not conform to the treatment and eliminate 1 case(see table 1). Full analysis of 72 cases, 67 cases of conform to the plan set. Observation group of 35 cases, control group 32 cases; Two group total effective rate comparison, the difference was statistically significant(P < 0.05), and significant clinical control, efficiency comparison, the difference was statistically significant(P < 0.05). Two groups of patients in clinical symptoms, signs andsyndromes were improved significantly(P < 0.05), significantly lower integral, observation group for each major project was observed and integral drop degree is better than the control group. Observation patient’s condition in a month time, knee X-ray improve the two groups was not obvious. Two groups of patients with blood, urine, blood sedimentation, routine, liver and kidney function, c-reactive white, electrocardiogram(ecg) during the period of observation has not been found serious abnormal or adverseConclusion: Juan bi particles treat type cold dampness bizu knee osteoarthritis is safe and effective, and can significantly improve the clinical symptoms, no significant side effects, can be used as a clinical medication for the treatment of osteoarthritis. Worth clinical application and promotion.