Clinical Effects Of Different Lntraocular Lens Implanted In Cataract Eyes With High Myopia

Objective: This study investigates the safety and effects of using BigbagIntraocular Lens （IOL）and Rayner620H IOL in cataract eyes with high myopia anddiscusses the safety and stability of these two IOLs within the eyes.Method:60cataract eyes with high myopia out of42patients who were admittedfrom January2012to June2013, were chosen in this study. The patients wereintroduced with the two lens indetails and, according to their different choices, thesepatients were divided into two groups:30eyes in group A using Bigbag IOL, and30eyes in group B using Rayner620H IOL. All the eyes in both groups underwentphacoemulsification with IOL implantation surgery by the same ophthalmic surgeon,and there were no complication like posterior capsular rupture. In this research, thepatients were assessed by visual acuity(VA), best corrected visual acuity(BCVA),optometric degree, intraocularpressure（IOP），axial length (AL), post-operativeposterior capsule cataract, vitreousopacity and thickness of fovea. The assessments weredone at regular intervals: preoperative stage and postoperative at one day, one week, onemonth and three months. All data were processed by using the SPSSS19.0softwarefor comparison of results within each group and between the two groups.Results:1. The postoperative VA and BCVA were higher than before operation within eachgroup, but there were no significant difference (P>0.05)if compared between group A and B.2. The postoperative optometric degree in each group decreased as compared tobefore operation (P<0.05). Postoperatively the actual optometris degree of each groupas compared with the reserved degree showed significant difference (P<0.05), while theactual optometria degrees measured in all stages showed no significant differencebetween the two groups (P>0.05).3. The average postoperative IOP change as compared preoperatively, revealed nosignificant difference (P>0.05) in both within and between the two groups.4. OCT examination demonstrates that the foveal thickness of group A increasedafter operation at each stage, but there were no significant difference when comparedwith before operation (P>0.05).In group B, the foveal thickness at all stages increasedwhen compared to preoperative data, and it showed significant difference (P<0.05).5. As for the AL measured before and after operation, there were no significantdifference in both group A and group B (P>0.05).6. At3months post surgery, there were no posterior capsular wrinkle in any of theeyes in group A, while posterior capsular wrinkle was observed in5eyes in group B,but there was no significant difference between the two groups(P>0.05).7. There were no significant difference of the postoperative posterior capsulecataract rate in group A and group B (P>0.05).8. At3months post surgery, there were no retinal detachment in group A, while ingroup B one eye got retina hole, and one eye got retinal detachment.9. At3months postoperatively, vitreous opacity increased in40eyes, as wasrevealed by questionnaire. The result was that there was significant difference betweenthe two groups (P<0.05).Conclusion:1. Phacoemulsification with IOL implantation is a highly efficient and securemethod for the treatment of cataract.2. Both Bigbag IOL and Rayner620H IOL are appropriate for cataract eyes withhigh myopia as the degree of myopia can be more precisely corrected. 3. Postoperatively, Bigbag IOL is more stable and has lower incidence of macularedema, and thus, more suitable for cataract patients with high myopia.