Traditional Chinese Medicine (TCM) Syndrome Differentiation With Finasteride Piece Of Clinical Research For The Treatment Of Seborrheic Alopecia

To explore Chinese medicine syndrome differentiation with finasteride tablets to treat male pattern hair loss basis and clinical curative effect,and to explore male pattern hair loss syndrome types of TCM clinical distribution and risk factors of disease cause,finding preventions and clinical treatment to provide theoretical support for male pattern hair loss.This research USES two groups of contrast, as traditional Chinese medicine (TCM) syndrome differentiation with finasteride pills contrast pure finasteride pills treating.By setting treatment curative effect observation during and after unified standard.Using the statistical methods to analysis each group before and after treatment in patients with symptoms of data.Eventually watch Chinese medicine syndrome differentiation with finasteride male pattern hair loss treatment clinical curative effect, and its curative effect difference with the control group.①With my families,60patients with male pattern hair loss as the case group, the other60patients of control group were studied.Case group and control group using uniform source sex hormone hair loss comprehensive investigate the curative effect observation table, content includes general information (gender, age, etc.), family history, nature of work, etc.and observation indexes including illness weight grading, the number of hair loss and scalp grease is secreted, extent of itchy scalp, dandruff, hair regeneration, serum free testosterone (FT).②Treatment group using evidence-based medicine for oral Chinese medicine, and comply with that male press1mg, once per day, oral.Control group only the male press1mg, once per day, oral.The groups use5%minoxidil topical solution at the same time.one month for a period of treatment,as the end of six months of treatment, to observe the curative effect of the two groups.To evaluate the overall effect according SSRI.Standard as:SSRI≤0.20; SSRI0.20-<0.60; SSRI≥0.60; In order to powerfully and effectively percentage of total effective rate of patients.③Statistical analysis using SPSS18.0statistical software.The statistical variables to be said as (x±s),Use the Ridit analysis level data,the comparison of two rate with χ2inspection; Measurement data using t test;and finally.The final evaluation of traditional Chinese medicine syndrome differentiation with finasteride according to relative advantages for the treatment of male pattern hair loss.Results:①General data results:A total of116cases of120cases completed the Clinical observation.The youngest19years old, the oldest36,The shortest duration of3months, the longest4.5years.The average age of treatment group is27.30±4.05y,The average duration is2.04±0.98y,The average age in the placebo group is26.93±4.00y, The average duration is2.06±0.92y.②Frequency analysis results:The disease has obvious genetic history,88cases with this disease as his father in116male patients, accounting for75.86%of the total sample size.Professional quality and psychological pressure is induced by contributing factors of the disease.Hair loss area concentrated expression in the forehead, accounting for70.8%.Type of traditional Chinese medicine shows that the distribution of hot and humid implication and hot air drying is given priority to with blood, and36%and35%respectively.Samples free serum testosterone is little higher than normal ceiling.③Single factor analysis showed that Psychological stress, the number of hair loss and fat levels, itching, and degree of scurf case group compared with control group, P>0.05, there was no statistically significant difference, you can compare. Incorporate the independent sample t test, the treatment group and control group after treatment difference is in addition to the degree of dandruff P values are less than0.05, the difference was statistically significant.④Two groups of curative effect comparison:Treatment group (18cases were markedly improved,28cases effective, the total effective rate was77.79%;Control group10cases had marked effect,17cases effective, the total effective rate was47.36%.⑤Results of two groups radit analysis:Mean Ridit z=2.31665, P=0.00686.The P value is less than0.05,The difference was statistically signif icant.Two group total effective rate (better+effective):The x2test shows that the difference was statistically signif icant,(x2=11-6351, P=0.00064<0.05).Conclusions:Seborrheic alopecia is the advantage of traditional Chinese medicine disease.Traditional Chinese medicine (TCM) syndrome differentiation with finasteride contrast pure finasteride pills treating male pattern hair loss,has an obvious advantage in alleviating symptoms and curative effect.Can obviously reduce number of hair loss, fat degree, degree of pruritus,㈧etc.But it does not reduce scurf.Clinical main syndrome type distribution is given priority to with hot and humid intrinsic type hot air drying and blood type.Family, psychological stress and sleep disturbance is the disease aggravating factor.