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Develop Intelligent Monitoring And Controlling System Of Bioreachor

Posted on:2015-01-20Degree:MasterType:Thesis
Country:ChinaCandidate:Y S WangFull Text:PDF
GTID:2268330428464412Subject:Electronics and Communications Engineering
Abstract/Summary:PDF Full Text Request
With the rapid development of society, modern biotechnology which is represented by geneticengineering, cell engineering, enzyme engineering and fermentation engineering widely used inmedicine, food, environment, marine, energy field and so on. And it shows great potential fordevelopment. Therefore, a large number of biotechnology research are carried out and researchersstart from the relevant biological processes to biological growth environment, to enhance thebiological process of looking metabolites access method, so research laboratory can be changed intoindustrial production for the gradual transition. Therefore, the study of control system with thebioreactor has become one of the focus of today’s social research. According to the actual needs of biological processes, To the complex biological reaction process asthe main line, this paper designs a DSP-based embedded control systems to meet the needs ofdifferent biological reaction process. The content of this paper mainly includes:Firstly, through reading the related literature, from the initial understanding of biotechnologyto in-depth understanding of biological reaction process, analyzing of measurement and controlsystem studies of existing biological reactor, summarizing demand of monitoring and controlsystem with bioreactor. According to actual testing needs of the biological process, DSP-basedmonitoring system is proposed as a bioreactor universal control system plan. To adopt PLC modulardesign idea, the use of embedded technology, the system is divided into three basic modules: themain control module, the detection module and the control module, with CAN bus, each modulejoins together to form a complete system, realization of temperature, pH, dissolved oxygen on-linedetection, at the same time, achieving additional acid, feeding, mixing and oxygenation,anti-foaming, heating and cooling control. Through the system of the flexible combination andupgrading, it can satisfy the application of different biological processes applications andimplement the intelligent of the system.Secondly, according to the system design scheme, system hardware and software are designed.Using DSP strong ability of operation, master control module design for the use of DSP embeddedsystem to manage the whole system of data, human-computer interface is designed by combiningDSP and CPLD hardware. Designing detection module signal conditioning circuit is to achieve thetemperature, pH and dissolved oxygen sensors weak signal acquisition, and to convert to a digitalsignal by MCU. And drive control module of external devices, the circuit achieve to heating andcooling control, acid and alkali control, fed control, mixing control, lighting control, design CANbus network structure and the application layer protocol, then to design software by the integrated development environment software,such as CCS (Code Composer Studio)、Keil and so on.Finally, system debugging, to achieve complete organism cultivation process and the overallsystem for test through the measurement and control system. On this basis, as the example of Pichiapastoris, Spirulina platensis, the researchers carried out biological pharmaceutical and biologicalexperiments in the field of energy and environmental bioremediation. After a few months, a fewbatch experiments proved: the system can maintain the culture temperature, pH and dissolvedoxygen in the best range of biological process. In the two pilot line, the system verify theapplicability of the new instruments and integrated systems.
Keywords/Search Tags:bioreactor, bioprocess, monitoring and controlling systems, DSP, CAN Bus, Modbus-RTU protocol
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