Epidemiological Survey Of Oral Symptoms In Patients With Primary Sjogren’s Syndrome

PURPOSE:To provide a theoretical basis for clinical prevention by surveying oral symptoms in primary sjogren’s syndrome (pSS) patients, counting and analysing the related factors atrophic glossitis, dental caries and periodontal diseases in pSS patients.METHODS:1.A retrospective study and comprehensive oral examination was conducted in93patients with pSS, and taked the tongue back photos, graded the level of the atrophy of tongue papillae on the back of the tongue. Clinical manifestation and oral symptoms were compared between the pSS patients with atrophic glossitis and without atrophic glossitis. The risk factors that may cause atrophic glossitis were analyzed by univariate and multivariable Logistic regression analysis and chi-square test.2. A random sample of107subjects without systemic disease and healthy persons as control group.Dental examination was conducted in93pSS patients recording the index of periodontal condition, caries, edentulous jaw.The healthy subjects without systemic diseases as control group.RESULTS:1. There were60patients in93pSS patients (64.52%) with atrophic glossitis. Dry mouth, and the duration of the pSS>4years were the risk factors of atrophic glossitis occurred in patients with pSS. Whether with dry mouth (OR=3.113) and the length of the course of the pSS (OR=3.402) affected the incidence of atrophic glossitis degree. There was a statistically significant difference between groups.2. PSS patients suffering from dental caries rate (97.81%) is significantly higher than control group (62.62%)(P<0.001); The mean of decayed missing filled tooth(DMFT) in pSS patients (10.70) is significantly higher than control group (2.78)(P<0.001); Severity of caries and duration of pSS were positively correlated (r=3.985, P<0.01); The periodontal condition and edentulous jaw in pSS patients had no significant difference with the control group.CONCLUSIONS:1. Atrophic glossitis is a common complication of pSS. Dry mouth and the length of the course of the pSS is risk factors affecting pSS patients with atrophic glossitis and aggravating atrophic glossitis. Cooperating with Department of Stomatology timely is important to control the development of atrophic glossitis.2. PSS patients are higher risk of dental caries and more serious than control group; Severity of caries and duration of pSS were positively correlated; PSS was no significant correlation with periodontal disease.