A Research About The Relationship Between Actinomycetes And Tonsillitis

Objective.To study the relationship between actinomyces and Chronic tonsillitis,the relationshipbetween actinomyces and tonsillar hypertrophy.To observe the expression of TLR2in thepharyngeal tonsil.To preliminarily search the mechanism of that actinomycetes infection results inpharyngeal tonsil’s diseases.Methods1066cases of illness during2010-2012about Chronic tonsillitis and tonsillar hypertrophywere amassed,a retrospective review were made to research actinomycetes infection rate indifferent group.46cases of illness with actinomycetes infection were amassed as group1,46cases of illnesswithout actinomycetes infection were amassed as group2.Then the expression of TLR2werecompared by immunohistochemical technique.IPP6.0image analysis software was used to countIOD.SPSS13.0for Windows was used for statistical analysis.ResultsThe actinomycetes infection rate of chronic tonsillitis is13.51%,the actinomycetesinfection rate of tonsillar hypertrophy is7.27%,which raised year by year during2011to2012.The expression of TLR2were detected in the intratonsillar cleft, the surface of tonsillar andgerminal center. The expression of TLR2in intratonsillar cleft of group1was significantlyincreased compared with group2(p<0.05).ConclusionsActinomycetes has close relationship with Chronic tonsillitis and tonsillar hypertrophy,whichmay lead to tonsil inflammation and hyperplastic tonsil.TLR2play an important role in themechanism of that actinomycetes infection results in pharyngeal tonsil’s diseases.