Beijing City Knee Osteoarthritis Dynamic Change Law Of Tcm Syndrome Research

Osteoarthritis has been one of common diseases in clinic for years and knee osteoarthritis ranks first in incidence and frequency of osteoarthritis. Knee osteoarthritis is characterized as a chronic aseptic repeated inflammation. KOA makes patients especially the aged people painful and destroys the happy lives of every family and harmony of society. Doctors of Traditional Chinese Medicine first cognized knee osteoarthritis when the great book The Inner Canon of Huangdi written thousands of years ago and quantities of experiments and cases were accumulated. The doctors have developed its own theory and a particular ways of diagnosing and treating the nettlesome disease. While lots of money and recourses had been invested and some remarkable developments in Genes Immunology and Biomechanics have been made in modern medicine which threw a glimpse of light to the research of KOA. The syndrome of KOA in TCM differentiation and the law of the syndrome of KOA in TCM transition remain unclear and no literature has argued about that. The doctors treat and prescribe the KOA patients based on their own treating experience and pattern in clinic and the lack of syndrome differentiation and treat variation makes the situation worse and worse. It is important and necessary to do some research in discovering the law.Objective:To observe the law of the syndrome of KOA in TCM transition as time going by and guide the clinical prescription.Methods:We invested KOA cases of citizens living around Yu Yuantan Hospital and Yue Jiyuan Community Hospital by telephone-interview and did a face-to-face cross-sectional questionnaire interview in September2012. We gathered the clinic TCM data and gave the patients a mark of KOA syndrome. We re-invested the patients and examined the transition of KOA syndrome every2months, when the weather changed. All the data from the qualified65cases were input the spssl9.0database. The cases were divided into4groups:Group1wind-cold-wet bi syndrome, Group2blood stagnation bi syndrome, Group3, the deficiency syndrome of liver and kidney and Group4wind-hot-wet bi syndrome, based on Clinic Patterns of9diseases of Orthopedics published by State Administration of Traditional Chinese Medicine of the People’s Republic of China. The data were analyzed by chi-square test in order to find out the law of the syndrome of KOA in TCM transition.Results:We invested79cases (79knees) and have completed65cases (65knees)1. The first interview showed that Group1wind-cold-wet bi syndrome, there were33patients included which contained10males and23females. Group2, blood stagnation bi syndrome there were22patients included which contained10males and12females. Group3, the deficiency syndrome of liver and kidney there were10patients included which contained3males and7females. There was no patients qualified in Group4wind-wet-hot bi syndrome.2. The second interview showed there was not any patients whose the syndrome of KOA in TCM altering in the Group1wind-cold-wet bi syndrome and Group3the deficiency syndrome of liver and kidney. There were7patients whose the syndrome of KOA in TCM turning out to the wind-cold-wet bi syndrome in the Group2blood stagnation bi syndrome.3. The third interview showed that there was1patient whose the syndrome of KOA in TCM changing to the deficiency syndrome of liver and kidney. There was3patients whose the syndrome of KOA in TCM turning out to the wind-cold-wet bi syndrome in the Group2blood stagnation bi syndrome. There was no change in the Group3the deficiency syndrome of liver and kidney.4. The different between the number of patients whose the syndrome of KOA in TCM changing in the wind-cold-wet bi syndrome and the blood stagnation bi syndrome (p=0.00) was statistics significant. Conclusion:The wind-cold-wet bi syndrome and the deficiency syndrome of liver and kidney did not change correlatively as time went by. The blood stagnation bi syndrome changed easier than the wind-cold-wet bi syndrome. The blood stagnation bi syndrome changed as time went by and this syndrome seemed likely to transmit to the syndrome wind-cold-wet bi syndrome.