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Cold Saline Solution And Sodium Hyaluronate Treat Knee Osteoarthritis And Curative Effect Observation Of Synovitis

Posted on:2013-09-04Degree:MasterType:Thesis
Country:ChinaCandidate:Y ZhangFull Text:PDF
GTID:2244330377455027Subject:Sports Medicine
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Objective: combined synovitis of the knee osteoarthritis studyprogress,the concept of built-in from the ice starting to explore the disease is morereliable,effective,economic,safe and simple treatment,in order to improve disease Theclinical efficacy and quality of life.Methods: included in the standard clinical admitted to osteoarthritis of the knee withsynovitis in patients with69cases,all cases in patients with informed consent,accordingto the consultation of the order,random number table,stratified randomizationmethod,single-blind divided into treatment and control groups,to suspend the course oftreatment,off,removed the two cases,accounting for2.90%of the total. Actually enrolledin the trial of cases to67cases. Treatment groups: low-temperature saline lavage&intra-articular injection of sodium hyaluronate in33cases (11males and21females,atotal of40knees); control group: at room temperature saline lavage&intra-articularinjection of sodium hyaluronate in34cases (17male and17females,a total of42knees).Test evaluation indicators: two groups of pain before and after treatment using a visualanalog scale the VAS (0to10) method to assess functional situation WOMAC andLysholm score table to assess; Formula points-before treatment points)/pre-treatmentpoints x100%(after treatment. Results:(1)The gender composition of the two groups,χ2test,P=0.676>0.05,no significantdifference,comparable.(2) two sets of left and right knee,the number of samples constitute,χ2test,p=0.860>0.05,no statistical differences were comparable.(3) the homogeneity of variance and t-test of the measurement data,the two ages: P=0.000<0.05,show that two groups of patients with the age distribution of a statisticallysignificant difference.(4) distribution of the two sets of knee function severity (WOMAC Franceratings),the correction for continuity test,P=0.309>0.05,no statistical differences werecomparable.(5) two groups of patients with treatment before the pain (vas score) to compare the p=.361>0.05,with homogeneity of variance,no statistical differences were comparable.The two groups of patients after treatment,pain (vas score),F=0.865,P=0.355; t=-1.619,P=0.109>0.05,95%confidence interval-0.504to0.052.(6) two groups of patients with knee function before treatment,the degree of recovery(France the WOMAC score),P=0.581>0.05,homogeneity of variance,no significantdifferences were comparable. The degree of recovery of knee function in two groups of patients after treatment (France the WOMAC score) to compare the F=2.956,P=0.089;t=-4.124,P=0.000<0.05,95%confidence interval-11.596-4.047; variance Qi,with asignificant difference.(7) of the two groups before treatment in patients with knee functional recovery(Lysholm score table),P=0.465>0.05,no significant differences were comparable. Thedegree of recovery of two groups of patients after knee function (Lysholm score table),F=0.204p=.653; t=1.419,P=0.159>0.05,95%confidence interval-1.296to7.798.(8) Minimum expectations two groups of patients with clinical treatment efficacyevaluation (Lysholm score table) P=0.689>0.05,no significant difference betweentreatment group was more efficient than the control group.Conclusion The clinical study showed that: the merger of the treatment and controlgroups used in clinical treatment of osteoarthritis of the knee synovitis have a bettertherapeutic effect,the treatment group knee pain relief,clinical efficacy and the controlgroup,the recovery of knee function than the control group; description of thelow-temperature saline knee joint cavity lavage with the injection of sodiumhyaluronate,is conducive to knee osteoarthritis merger effective treatment of synovitisof knee function recovery is an ideal,safe,reliable,practical and clinical treatment,whilea certain extent,enhance the clinical effects,and prevent and reduce the recurrence ratecombined synovitis of the knee osteoarthritis.
Keywords/Search Tags:low-temperature saline, sodium hyaluronate, lavage, intra-articularinjection
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