Objective:the evaluation GubentiaofeiTreatment of chronic obstructive pulmonary disease, stable lung spleen deficiency syndrome and clinical efficacy, and initially to explore its possible mechanism.Methods:There were60cases of chronic obstructive pulmonary disease with stable lung in patients with spleen deficiency syndrome met the inclusion criteria were randomly divided into plus and Western medicine with traditional Chinese medicine group (30cases) in the control group (30cases),two groups of1:1. On the basis of the treatment group in the tiotropium bromide powder inhalation and oral aminophylline sustained release tablets Gubentiaofei prescription with traditional Chinese edicine, the control group were thiophene tiotropium powder for inhalation and aminophylline sustained release tablets, treatment of each the clinical efficacy of the two groups were observed in the continuous three courses to four weeks, Chinese medicine symptom efficacy, quality of life score, serum tumor necrosis factor changes, and followed up for6months. Obtained information to adopt SPSS17.0software for statistical analysis.Results:(1) Strengthening the economy adjust lung prescription to the treatment of chronic obstructive pulmonary disease stability of the lung in patients with spleen deficiency syndrome, compared with the control group, to reduce symptoms, improve mobility and reduce the St. George’s score value than the control group (p<0.05) integral reduce the TCM symptoms than the control group (p<0.01) increase in their body mass index than the control group (p<0.05). Improve patients’quality of life, slow down the disease progression of COPD.(2) Before and after treatment of lung function difference was not significant.(3) Strengthening the foundation Gubentiaofei prescription to the treatment of chronic obstructive pulmonary disease stability of the lung in patients with spleen deficiency syndrome can significantly reduce the serum levels of tumor necrosis factor levels (p<0.01), to reduce the number of hospitalizations (p<0.05) compared with the control group, and can significantly reduce the total hospital days (p<0.01), to improve the nutritional status and prognosis.Conclusion:The the Gubentiaofei Treatment of chronic obstructive pulmonary disease with stable lung spleen deficiency syndrome can significantly improve patients’clinical symptoms and quality of life better than the comparison group, and in the process of delaying COPD, safe and effective is worth further research and promotion. |