The Clinical Observation Research On The Treament Of Of Chronic Obstructive Pulmonary Diease Of Spleen And Lung Deficiency Type In Stable Period With The Costusroot And Amomum Six Gentlemen Decoction

Object:To explore the effects of Costusroot and Amomum Six Gentlemen Decoction in the treatment of stable COPD complicated with malnutrition,TCM Syndrome Differentiation for lung and spleen qi deficiency patients curative effects and possible mechanisms of action.Method:60cases of stable COPD patients complicated with malnutrition were randomly divided into two groups:the treatment group and the control group, both with30cases. The control group with salmeterol and fluticasone propionate powder inhaler (hereinafter referred to as the Seretide inhalation)50/250ug,2times a day, the treatment group of Six Gentlemen Decoction Combined with the action of seretide in the treatment, the course was3months. Observe two groups of symptoms, nutrition indexes including body mass index (BMI), ideal body weight(%IBW), mid arm ciricumference(AMC),triceps skinfold(TSF),mid arm muscle ciricumference(MAMC), and serum indexes of serum albumin, prealbumin, lymphocytopenia, respiratory function, quality of life nutrition index.Results:(1) The total effective rate of the treament group was86.7%, while60.0%of the control group.There was significant difference between two groups (P<0.05), suggests that the treatment group in the total efficiency was significantly better than the control grou.(2)In two groups after the treatment, TCM syndrome had a significant difference (P<0.05), the treatment group was superior to control group in improving symptoms.(3) In two groups after the treatment, nutrition indexes and serological index had a significant difference (P<0.05), the treatment group was better than the control group in improving nutrition.(4) After treatment, two groups of dyspnea score, the score of life quality were improved, the treatment group in the degree of improvement compared to the control group, the differences were statistically significant (P<0.05).Conclusion:The action of Costusroot and Amomum Six Gentlemen Decoction in the treatment of COPD stable period of malnutrition (spleen qi deficiency) patients, by strengthening spleen and tonifying the lung, improved the nutritional status of patients, lung function and the quality of life of patients.