The Relation Between The Serum HbA1c Level And Coronary Lesions In The Patients With Hypert Ension

Objective: To explore the correlation between the level of serumglycosylated hemoglobin A1c(HbA1c) and the severity of coronaryatherosclerotic lesions in the patients with hypertention.Methods: Total81patients with hypertention were admitted in our study.All the patients agreed to undergo selective coronary angiography using64-slice CT and serum HbA1c concentrations. According to the level ofserum HbA1c concentrations, the patients were classified into low HbA1clevel group(HbA1c＜6.5%) and high HbA1c level group(HbA1c≥6.5%),between which the extent of the coronary stenosis and the quality of thecoronary atherosclerotic lesions presenting on CT were compared. Thecontrol group was consisted of41patients with serum HbA1c level＜6.5%and without hypertention, dyslipidemia, hyperglycemia orhypoglycemia, all of whom also underwent the examinations mentionedabove.Results:1. There was significant difference in the extent of the coronarystenosis and the quality of the coronary atherosclerotic lesions presentingon CT between either hypertention groups which were the low HbA1c level and low HbA1c level group and the control group (P＜0.05).2. No significant difference was found in the extent of the coronarystenosis or the quality of the coronary atherosclerotic lesions presentingon CT between the low HbA1c level group and the high HbA1c levelgroup (P＞0.05).Conclusion: There was no correlation between the serum level ofglycosylated hemoglobin A1c(HbA1c) and the severity of coronaryatherosclerotic lesions in the patients with hypertention...