The Clinical Research In The Treatment Of Acute Exacerbations Of Chronic Obstructive Pulmonary Disease Based On The Of Lung Disease To Cure Intestine

Objective:To observe the clinical effects of xuanbaichengqi soup in the treatment ofAcutely Exacerbate Chlonic Obstruetive Pulmonary Disease(AECOPD); To study itsmechanism of diarrhea in patients with chronic obstructive pulmonary disease(COPD),andto provid the new clinical foundation of Treating AECOPD by Chinese Medicine.Methods:Sixty hospitalized AECOPD patients with retention of randomly dividedinto two groups which is30patients each group,the trial group and comparativegroup.Treat both two groups with oxygen treatment under control,anti-infection,facilitating expectoration,relieving dyspnea and spasm by western medicine.The trial groupis in regular treatment by western medicine, and drink the xuanbaichenqi soup for a courseof treatment which lasts for7days,Observe the patients’change after the course oftreatment of their symptom and body character, Chinese Medicine symptom and character,lung function,white blood cells, The proportion of neutrophils and C-reactive protein.Conclusion:1.the general effectiveness of the trial group is93.33%,and thecomparative group is76.67%.The comparison between two groups’general effectiveness isdistinct (p<0.05).According toThe Chinese Medicine symptom integral,It shows thattreatment effectiveness of the the trial group is better than the comparative group.2.The symptom of cough,sputum,shortness of breath,abdominaldistension,astriction,moistrale and rhonchus were significantly improved compared withcontrol group (P<0.05).In the respect of improving lung function,comparing with beforetreatment,There were not significant differences(P>0.05);in both group separately aftertreatment,There were not significant differences(P>0.05).4.After therapy,amount of whiteblood cells,and proportion of neutrophils were lower than those before therapy,and thedifference was significant(P<0.05);After therapy,the white blood cells,and proportion ofneutrophils of treatment group was lower than control group and there was statisticdifference tetween two groups (P<0.05).5.After therapy, C-reactive protein were lowerthan those before therapy,and the difference was significant(P<0.05);Aftertherapy,C-reactive protein of treatment group was lower than control group and there wasstatistic difference tetween two groups (P<0.05).Conclusion:xuanbaichenqi soup collaborative western medicine can improveAECOPD patients clinical symptoms and signs,reduce amount of white blood cells andproportion of neutrophils effectively,which mechanism may give evil trends way out,unobstructed intestinal canal Qi function,give out heat and muddiness,make lung qi down,reduce phlegm and relieve asthma.The clinical effectiveness is very distinct,and no badreaction.It provides the clinical foundation to the AECOPD syndrome of phlegm-heat andnew treatment to the AECOPD.