Monitoring Analysis And Investigation Of Risk Factors Of Perinatal With Inborn Chilopalatognathus Disease In Hengyang During2002and2009

ObjectiveExploring the incidence rate of inborn chilopalatognathus,its dynamic statechanging and its risk factors during the2002and2009, in order to provide referencefor improving the quality of the birth population.MethodsCollecting the monitoring data of perinatal infant inborn chilopalatognathusfrommaternity and child care centers and hospitals in the city of Hengyang during2002and2009years. To master its the incidence situation and trend of the popular andanalysise the incidence state of inborn chilopalatognathus, and the different ofincidence rate of inborn chilopalatognathus in sex, urban and rural and different ageof pregnant women by chi square test;Matched case control study of1:2, choosing theinborn chilopalatognathus and normal infants with their parents from maternity andchild care centers and hospitals in the city of Hengyang. Designed the questionnaire.Matched case control study of1:2was designed for exploring risk factors of theinborn chilopalatognathus disease. Then used univariate and Multi-factors Logisticregression analysis, and Multi-factors which can classification entered regressionequations were classified analyzed. The data were analyzed by spss18.0.Results1.236340perinatal infant were monitored during2002-2009years, as a result,359perinatal with the inborn chilopalatognathus disease were found. Over the last8years, the average incidence of the inborn chilopalatognathus disease was15.19in every ten thousand in Hengyang city, and had an upward trend (P=0.002) bychi square test. 2. The incidence of male was17.51in every ten thousand, female was9.57in everyten thousand, the difference was significant (P=0.000).3. The incidence of urban was9.05in every ten thousand, the rural was17.89inevery ten thousand, the difference was significant (P=0.000).4. The incidence of four seasons respectively was25.32,9.24,9.63,19.32in everyten thousand, the difference was significant (P=0.031).5. The incidence of age of under20years、20～、25～、30～and up35years41.43、15.22、12.96、14.94and48.58in every ten thousand respectively, the differencewas significant (P=0.000).6. The single factor analysing of the inborn chilopalatognathus Disease, vegitableand fruits, dringking milk,frenquency of bean food of pregnant women weresignificant protection factors. Pregancy times,cold history in the first threemonths of pregnancy, bad mood, wedding for medical, harmful materialcontact,the reproductive system infection history, abortion history, husbandsmoking and drinking, contacting benzene material, contacting the pesticide,fertilizer, taking sulfa drugs, taking antibiotic medicines and service antiviraldrugs, taking sugar cortical hormone drugs, the family inheritance history, parentsblood types, cousins marry history were significant risk factors. And then didmulti-logistic regression analysis, dringking milk and frenquency of bean food ofpregnant women were protictive; contacting harmful material,taking sugarcortical hormone drugs and family history。Conclusion1. The incidence of inborn chilopalatognathus disease had an upward trend during2002and2009years in Hengyang city.2. The females incidence of inborn chilopalatognathus disease was higher thanmales’s.3. The rurul incidence was higher than city’s between2002and2009; The incidence in winter and spring were higher than summer and autumn’s.4. The age of pregnant women lower than20and equal or higher than35was high stage in the incidence of inborn chilopalatognathus. 5. The risk facors of inborn chilopalatognathus disease were pregancy times,cold history in the first three months of pregnancy, bad mood, wedding formedical, harmful material contact,the reproductive system infection history,abortion history, husband smoking and drinking, contacting benzene material,contacting the pesticide, fertilizer, taking sulfa drugs, taking antibiotic medicines and service antiviral drugs, taking sugar cortical hormone drugs, the family inheritance history, parents blood types, cousins marry history.6. Drinking milk and bean foods frequently during pregnancy were the protective factors.