| Objective: To determine the prevalence and influencing factors of Urinary calculi, to explore the inter-relationships between urinary stone disease and various risk and protective factors and to determine the potential implications for intervention sand prevention in Guangzhou panyu, and evaluate the relative importance of each risk factor, then provide scientific guidelines for Urinary calculi 'S prevention and Diagnosis, To explore the inter-relation ships between urolithiasis and various factors and to determine the potential implications for prevent ion.Methods: case—control study was designed, in which Cases and controls 'd interviewed with the same questionnaire. Firstly, Conducting univariate conditional Logisti cregression analysis to filtera It her esearch factors. Then using multivariate conditional Logistic stepwise regression to filter once more, interactions were involved, establishing and valuating the o- ptimal regrssion model. With the hospital-based case-control study, 79 patients with idiopathic urolithiasis were collected as cases and 104 pa-tients without any urinary disease swere selected as controls Cases w erec hosenfr om thosew how ered iagnoseda si diopathic urinary calculi during the six month after we began the survey in the Red Cross Hospital of Shenzhen and the total number was 241. Controls are chosen from those who were hospitalized at that hospital at the same periodo fti mea ndh avert ou rinary ando stealdi seases. C ontrolsa rematch one by one with cases according to age, sex and hospitalization time. Subjects were investigated with a standard questionnaire to inquire their demographic features, health characteristics, family condition, working and living environment, diet, body shape and the like. Data are analyzed according to their respective property: two-dichotomous variable with matched fourfold table McNemar x z test; quantitative variables with matched t test and multifactor analysis of variance; discrete variables wiResults: With mult i2variate Logist ic regression analyses, the influencing facto rs fo r urinary calculiw ere dietary intake variables including mo re intake ofp ro tein (P＜0.05), fat (P＜0.05), pho spho ms (P＜0.05), carbohydrate (P＜0.05), dietary fibre (P＜0.05) and vitam in C (P＜0.05), and dietary habit variables including drink ing lessw ater (P＜0.05), salted taste (P＜0.05), and higher fam ily income per cap ita (P＜0.05)Conclusion: Dietary habits and nutrition intakes were most important factors associated with Urinary calculi, The positive family history of urinary stones could increase the risk of stone formation but the role of the positive family history is less important than economic factors were. also associated with the disease. The that of the environmental factors. D i-etary habits and nutrition intake are most important factors associated with urolithiasis. The posi-tive family history with urolithiasis and family income increase the risk of urolithiasis. Volta ge wasc ontrolleda t2 OK V andc urrentfl uctuatea tl 40uA. The temperature in compartment was controlled at 25C. Capillary wasrinsed with 1 M NaOH, distilled ater and buffer before running samples. Calibration curves were alculated from injection of five different levels (10-250mg/L) of standards. Peak height and time-corrected area were used for quantitation. Th ea na lysist imei sa bout10m ina ndt herei sn oi nterferencei nelectrophoretogram. The oefficient of correlation between concentration and peak area is more than 0.9998. The detection limits are 1.5 mg/L for creatinine and 0.7 mg/L for uric acid. The coefficient of variation of peak area is 3.05% and that of migration time is 0.36%. The recovery rate is between 97 and 107%. |
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