Acupuncture At Different Matching Acupoint On Model Rats With Constipation Bowel Movement Regulation Mechanism

Purpose: Through the copy rats constipation model, by elisa to studying blood serummotilin and gastrin in rats expression changes and the impact of acupuncture on them, revealthe mechanism of the prevention of constipation acupuncture gastrointestinal endocrinologyThrough the acupuncture points of different combination stimulating bowel movementsregulation Clinical point for compatibility and meridians formula to provide valuableinformation for acupuncture point, organs closely related theory provide experimental data.Method:72Wista rats were randomly divided into6groups: normal control group,model group, grab bound group, same ganglion group, different ganglion group, sameganglion and different ganglion group. The constipation model uses the medicine CompoundDiphenoxylate given by intragastric method to make the model replicate; normal controlgroup feeds normally, does not carry on processing; grab bound group: after made mode,daily grab bound; same ganglion group to take “Tianshu Point” with on “Dachangshu Point”;different ganglion group to take “Quchi Point” with on “Shangjuxu Point”; same ganglion anddifferent ganglion group to take “Tianshu Point”“Dachangshu Point”“Quchi Point” withon “Shangjuxu Point”. Record each group’s first bowel movement time after time’sadministration, the collection and the record of administration latter12hours the excrementnumber of seeds and the excrement weight, and take4day-long accumulation quantity as theobservations. After the experiment, extract the rats of blood serum of abdominal aortic ofdifferent groups using ELISA technology, observe the acupuncture point with different on ratMTL and GAS in serum, the influence of change.Result:1the first time bowel movement time of the rats, the model group and thenormal control group comparison has the significance difference(P<0.05), C D E F grouphas the significance difference comparison with the normal control group (P<0.05), but withthe normal control group comparison has no significance difference(P>0.05).2Bowel movement number of seeds index in rats, the model group and the normalcontrol group comparison has the significance difference(P<0.05), there is no significancedifference(P<0.05) between the model group and the grab bound group(P>0.05), the D E Fgroup has the significance difference comparison with the model group(P<0.05), the D group and the E group comparison has no significance difference(P>0.05), the D group and the Fgroup comparison has the significance difference(P<0.05), the E group and the F groupcomparison has the significance difference(P<0.05).3Bowel movement weight index in rats, the D F group has the significance differencecomparison with the model group(P<0.05), the E group and the model group comparison hasno significance difference(P>0.05), the E group and the D group comparison has nosignificance difference(P>0.05), the E group and the F group comparison has the significancedifference(P<0.05).4MTL of blood serum in rats, the model group has the significance difference witheach group(P<0.05); the model group and the F group comparison has no significancedifference(P>0.05), but has the significance difference with the other group(P<0.05); the Egroup and the D group comparison has no significance difference(P>0.05), the D E group hasthe significance difference comparison with the F group(P<0.05).5GAS of blood serum in rats, the model group and the normal control groupcomparison has the significance difference(P<0.05), the D group and the F group comparisonhas the significance difference(P<0.05), the D group and the E group comparison has nosignificance difference(P>0.05), the E group and the F group comparison has no significancedifference(P>0.05).Conclusion:1Effect of acupuncture on treatment of colorectal disorders has obvious,Therapeutic effect of acupuncture in treating constipation exact.2The same ganglion and different ganglion group of model with constipationimprovement effect in bowel movement number of seeds index bowel movement weightindex and motilin gastrin of rat’s serum, has obvious regulating action to only use sameganglion point or only use different ganglion point.