Etiology And Diagnosis Of Chronic Pancreatitis

Objective: To analyze the causes of CP, clinical feature,complication,the diagnosisof CP in our hospital．To discuss the different causes of CP about the diagnosis of CP inorder to supply advice in the further．Methods: A retrospective analysis the clinical dataof the468CP cases diagnosed by clinical, which from the First Affiliated Hospital ofXinjiang Medical University from January2004to August2011. To compile statistics theclinical manifestations, complications, laboratory examination and imaging examination,material, calculation of all the patients of constituent ratio. To compared the same periodto hospital patients with pancreatic diseases without controlled, the subjects (ROC)analysis work curve of CP diagnostic methods of sensitivity and specificity, all statisticalanalysis by SPSS16.0software process.Results:(1). The billiard system factor was theprimary cause of disease in these cases, accounting for38.5%, the secondary cause ofdisease was alcoholic factor, accounting for27.8%. Besides other causes of diseaseincluded Smoking (14.1%), hyperglycemia(9.4%), CP after acute pancreatitis(10.7%), CPafter the trauma of pancreas(0.9%), idiopathic CP(21.4%).(2)The main clinicalmanifestation was abdominal pain with404patients (86.3%),172patients (36.8%) withreferred pain, abdominal distension had96patients (20.5%). The main physical sign wasabdominal tenderness which had106cases(22.6%)，in these204cases the blood sugarraised had38cases(8.1%), the serum amylase rised had24cases(5.1%), the amylase inurine rise had42cases(9.0%), also together with tumor markers rised in some patients.(3)In these cases the imaging finding mainly were type-B ultrasonic, CT and MRCP, inwhich the type-B ultrasonic had316cases(62%),420of them used CT (76.2%),170ofthem used MRCP(82.4%). All kinds of diagnostic methods of diagnosis sensitivity andspecificity were B to exceed (64.6%and78.1%), abdominal CT (57.6%and80.0%),MRCP (60.0%and82.8%). Conclusion: The chronic pancreatitis caused by billiarddiseases were obviously more than the chronic pancreatitis caused by alcoholic factor. Imaging examinations play an important role in the diagnosis of this disease. B-us, CTand MRCP were the main imaging text in the diagnosis of the chronic pancreatitis. Thepositive rate of CT was obviously higher than the B-us. The positive rate of MRCP wasobviously higher than the type-B ultrasonic and CT.