Analysis Of The Etiology And Clinical Features Of Recurrent Acute Pancreatitis

Purpose: This article aims to analyze and explore the etiology and clinical features of recurrent acute pancreatitis and improve the diagnosis and treatment level of RAP.Methods: This study collected a total of 511 patients with acute pancreatitis(AP)who were hospitalized in the Affiliated Hospital of Qingdao University from January 2015 to December 2018.The clinical data of the patients were collected comprehensively,and telephone follow-up,outpatient or hospitalization were used.Follow-up review method.According to the frequency of AP,the patients were divided into a single group and a relapse group.The general data,clinical characteristics,etiology,laboratory tests,and risk factors between the two groups were analyzed and compared.The number of relapses between men and women in the relapse group was also analyzed.3.Analysis and comparison of relapse time.SPSS 22.0 software was used for statistical processing.T-test was used for comparison of measurement data in accordance with normal distribution.Chi-square test was used for comparison between count data.Logistic regression analysis was used for risk factor assessment.P <0.05 was considered statistically significant.Results: A total of 511 patients with AP were collected in this study.Comparison of general data: the average age of the single-shot group was 45.3 ± 14.12 years old;the average age of the relapsed group was 48.2 ± 15.65 years old;the average age between the two groups was not statistically significant(P> 0.05);the single-shot group had 406 cases(79.5%),male 240 cases(59.1%),166 cases of women(40.9%),105 cases(20.5%)of relapse group,65 cases of men(61.9%),40 cases of women(38.1%),there was no statistically significant difference in gender between the two groups(P> 0.05);Comparison of etiology: 169 cases(41.6%)of bile origin,87 cases(21.4%)of alcoholic,73 cases(18.5%)of hyperlipidemia,and 49 cases of idiopathic(P> 0.05)12.1%),26 cases(5.4%)with other factors;40 cases(38.1%)of bile origin in relapse group,21 cases(20.0%)of alcoholic,25 cases(23.8%)of hyperlipidemia,idiopathic 14 cases(13.3%),other factors(4.8%),hyperlipidemia factors were statistically significant between the two groups(P <0.05),biliary,alcoholic,idiopathic,and other factors There was no statistical significance between the groups(P> 0.05);in the comparison of laboratory tests,cholesterol,triglycerides,and blood glucose were statistically significant between the two groups(P <0.05);Comparison of the severity of the disease between the groups: 182 cases(44.8%)of MAP in the single group,133 cases(32.8%)of MSAP,91 cases(22.4%)of SAP;61 cases(58.1%)of MAP in the relapse group,There were 23 cases(21.9%)of MSAP and 21 cases(20.0%)of SAP.The comparison between the two groups was statistically significant(P <0.05);the comparison between smoking,obesity and diabetes was statistically significant(P <0.05);Logistic regression analysis showed that smoking,obesity,diabetes,and hyperlipidemia were risk factors for the occurrence of RAP(P <0.05);The patients in the relapse group,67(63.8%)had one recurrence,38 patients(36.2%)with more than one recurrence;69 patients(65.7%)relapsed within 1 year,36(32.3%)relapsed after 1 year.Conclusion: 1.RAP occurs mainly in middle-aged people,mainly males.2.The main causes of RAP are biliary,hyperlipidemia and alcohol.3.Smoking,obesity,diabetes and hyperlipidemia are risk factors for RAP.4.Most of RAP occur within 1 year of AP onset,and most of RAP recur once.