| Objective: Professor Zhang Minghe research in rheumatic autoimmune diseases for many years, in the treatment of osteoarthritis has formed a unique treatment considerations. Examined the effects of YISHENXIAOBI Treatment of knee osteoarthritis clinical efficacy, from the basic theory and clinical observation of two aspects of a study to examine the possible mechanism. Methods: 60 patients were randomly divided into 2 groups, respectively, using YISHENXIAOBI side, the two methods of oral music song treatment of knee osteoarthritis, observed symptoms, signs and laboratory test changes. Results: 1. Clinical Comparison of two groups: The total effective rate was 100% in the control group, the total effective rate was 90.00%, both groups had significant clinical difference (p <0.05); 2. TCM symptom score before and after treatment Comparison: the treatment group than the control group, there was significant difference between the two (p <0.05); 3. the two groups showed no significant safety differences.Conclusion: YISHENXIAOBI side of knee osteoarthritis with good clinical efficacy in relieving symptoms, improving joint function, improve quality of life has a better effect, and no adverse reactions. Combined with modern medicine, traditional Chinese medicine research and analysis of modern pharmacology, and its mechanism may be through anti-infective, anti-inflammatory analgesic, regulate immune function, improve blood flow changes so many aspects of osteoarthritis of the knee to play an effective therapeutic effect. |
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