| Object:To evaluate the efficacy of traditional Chinese medicine for subacute thyroiditis (SAT) and chronic lymphocytic thyroiditis (CLT); To mine and summarize the academic experiences on diagnosis and treatment of SAT and CLT of professor ZiXiao Wei, practising the use of data mining in inheriting the experiences of famous TCM doctors.Method:46 cases diagnosed and treated by professor Wei, including 61 clinical datas, were collected by structural clinical data collection system designed by Xiyuan Hospital of China Academy of Chinese Medical Sciences. Data mining methods such as descriptive statistics, association rules, cluster analysis were used to mine the distribution of syndrome elements, relations of diseases, syndromes and and Chinese medicinal herbs, compatibility law of traditional Chinese medicine. Finally, the academic experiences on diagnosis and treatment of SAT and CLT of professor ZiXiao Wei were summerised by human-computer cooperation.Result:There were 61 outpatients in the study:subacute thyroiditis(SAT) patients were 29 and chronic lymphocytic thyroiditis(CLT) patients were 32. There ware 23 female person-time in SAT group (79.3%) and 6 male person-time in SAT group (20.7%).The cardinal symptoms were the Pain in thyroid gland(51.7%), Insomnia(31%), flustered(27.6%), Thyromegaly(27.6%), hyperpyrexia(27.6%), dry stools(24.1%), low grade fever(24.1%), acratia(20.7%) and sore throat(17.2%).The tongue manifestation were fat tongue body(41.4%%), red Tongue Proper (82.7%), thin and white Tongue musci (51.7%%), yellow Tongue musci (34.2%). Diagnosis(TCM) were:Yingtong(72.4%), Yingzhong(72.4%), Bumei(6.9%). Therapeutic Methods(TCM) were eliminating stagnation(93.1%), Clearing Heat(89.7%), Detoxication (TCM) (69%), disperse wind(51.7%), tranquilization(37.9%) and Nourishing Yin and Blood(27.2%). There were 95 types of Chinese herbs to be used. The most use to prescription were Hedyotis Diffusa, Taraxacum, Great Burdock Achene, Rhizome of Paniculate Bolbostemma, chrysanthemum indicum, honeysuckle, Bombyx Batryticatus, Licorice Roots Northwest Origin, Grassleaf Sweelflag Rhizome, Forsythia.There ware 30 female person-time in CLT group (93.8%) and 2 male person-time in CLT group (6.3%).The cardinal symptoms were the acratia (37.5%), Insomnia(31.3%), dysphoria (28.1%), dreaminess (25%), Pain in thyroid gland (25%), dropsy (25%), ]sweating (25%), flustered(21.9%), and discomfort in the throat (18.8%). The tongue manifestation were fat tongue body with indentation (40.4%), dark red Tongue Proper (46.9%), thin and white Tongue musci (51.7%). Diagnosis(TCM) were:Yingzhong(50%), Yingtong(18.8%), Xinji(12.5%), Consumptive Diseases(9.4%), Edema(9.4%,), Bumei(6.3%), Melancholia(3.1%). Therapeutic Methods(TCM) were eliminating stagnation(59.4%), Clearing Heat(56.3%), Detoxication (TCM) (28.1%), Nourishing Yin and Blood(28.1%), Soothing-Liver Regulating Qi (28.1%), tranquillization method (25%), fortify the spleen and replenish qi (21.9%) and resolve phlegm (15.6%). There were 107 types of Chinese herbs to be used. The most use to prescription were Hedyotis Diffusa, Taraxacum, Radix Scrophulariae, Rhizome of Paniculate Bolbostemma, Indicum, Radix Curcumae, Rhizoma Atractylodis, Radix Bupleuri, Largehead Atractylodes Rh, Tuckahoe.Conclusion:1,Prof Wei Zi-xiao think the SAT and CLT are different disease in West medicine, but in TCM the pathologic mechanism is similar, that is affection of exogenous wind-heat. The reason is the SAT and CLT have the close same symptoms and same location. For this reason, Professor Wei based the Different Diseases in Same Treatment in Therapeutic Principles(TCM), treat the CLT and SAT by Clearing Heat, Detoxication (TCM) and eliminating stagnation;removing stasis.Preventive Treatment of Disease is an other very important point. TCM disease prevention first is a Philosophy in TCM Preventive Treatment of Disease. Prof Wei pay more attention to this point. Based the "Clearing Heat", treat the SAT and CLT is different. 2,The Excavation Methods based man-machine integration is favourable apply prospect in the Famous Doctors Experience impart and inherit. |