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Patients With Breast Cancer Surgery Syndrome Characteristics Of Study

Posted on:2011-12-24Degree:MasterType:Thesis
Country:ChinaCandidate:G F PeiFull Text:PDF
GTID:2204360305972543Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Breast cancer is the most common malignancy of women in recent years, the incidence is rising, especially in our growing problem of breast cancer, the incidence rate and mortality rate of growth than developed countries, causing physical and mental health of Chinese women risk. Chinese medicine has a long history of breast cancer, breast cancer patients in improving quality of life and prolong survival, reduce side effects such as chemotherapy and has a considerable advantage. This study aims to explore the application of Integrated Traditional and Western methods of breast cancer, the progress and outcome, the syndrome of menstrual factors and circumstances, TNM stage, lymph node metastasis, receptor, gene combination, reveals its intrinsic relevance, to guide the treatment of clinical differentiation therapy.Research Objective:Study and discuss Tradition Chinese Medicine pathogenesis of breast cancer and features of Tradition Chinese Medicin syndromes of Breast Cancer patients after operation.Methods:Through Prospective cohort study, designed observation forms are included in the study on patients with syndrome differentiation type, and benign and malignant breast disease syndrome between clinical change after breast cancer surgery, breast cancer syndrome factors and menstruation, TNM staging, lymph node metastasis, receptor, gene and other related factors were analyzed. Case count information on the use of SPSS 16.0 software x2 test methods and non-parametric test.Results:1,Be included in the study of 129 patients with breast cancer are false is mixed syndromes, in which Yang Qi deficiency with other syndromes are 99, yin and blood deficiencyith other syndromes are 30. Shows that the composition of the studied patients with Yang Qi deficiency accounts for the main component. Yang Qi deficiency+liver Qi stagnation,> Yang Qi deficiency+phlegm> yang qi deficiency+qi stagnation+phlegm> Yang Qi deficiency+Blood Stasis> Yang Qi deficiency+liver Qi stagnation, blood stasis> Yang Qi+Phlegm+blood stasis> yang qi+qi stagnation +phlegm card> Yang Qi+phlegm card;> Yin blood deficiency+liver Qi stagnation,>Yin blood deficiency+blood stasis> Yin blood deficiency +liver Qi stagnation, and Yin blood deficiency+phlegm.2,On benign breast disease and breast cancer risk analysis of age and stasis that the younger age of onset benign disease; to analyze and compare the two cards syndromes, Yang deficiency, qi deficiency and phlegm in the breast cancer group more common than benign breast disease group.3,41 cases of breast cancer before and after stasis, tongue, pulse compared to analyze the changes that patients with early breast cancer before surgery, righteousness weak, evil is not flourish, disease location is not deep, with deficiency mixed with more common; surgery increased significantly with deficiency, yang deficiency, qi deficiency more pronounced, so patients with yang, Qi Fu Zheng treatment mainly to dispel evil than to go out.4,elements of breast cancer syndromes in Chinese medicine and cancer biology with clinical pathology analysis of indicators, statistics, found that breast cancer menstruation, TNM stage, lymph node metastasis, ER, PR, P53 and qi stagnation, blood stasis, phlegm wet, Yang Qi, Yin blood deficiency syndrome elements, etc. There was no significant correlation, not as a type of syndrome differentiation factor; breast empirical evidence Hou elements and Her-2 showed no significant correlation, and Deficient Hou factor relevant.Conclusion:(1) Pre-operative breast cancer patients with the vacuity of the syndromes characteristic elements of the syndrome to yang deficiency, qi deficiency, limits the research to liver qi stagnation, phlegm, blood stasis syndrome based.(2) Compared with benign breast disease group, Yang deficiency, Qi deficiency and phlegm are more common in the breast cancer group than benign breast disease, though adjusting this benign breast disease by Traditional Chinese Medicine, can preventing the occurrence of breast cancer.(3) Breast cancer patients before surgery, righteousness weak, evil is not flourish, disease location is not deep, with deficiency mixed with more common, the body is empty, partially substantiated; surgery to reduce local real evil, deficiency increased, yang deficiency and qi deficiency are more significant Therefore, patients with yang, Qi Fu Zheng-based treatment to remove more than the evil out.(4) Her-2 positive rate have no significant correlation with Solid syndrome factor, yang deficiency and qi deficiency have correlation with Her-2 positive rate, Her-2 expression have higher positive rate, suggesting that Yiqiwenyang drugs could be improved patients prognosis.
Keywords/Search Tags:Etiology and pathogenesis, breast cancer, correlation, syndromes
PDF Full Text Request
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