Nephron - Paste Clinical Study On Acupoint For Treatment Of Chronic Nephritis

OBJECTIVETo observe the curative effect and safty of baoshen' gao to treat chronic glomerulonephritis(CGN)(insufficiency type of kidney-Yang , insufficiency type of kidney-Yin)by point application,and search an specific effective feasible method in treating CGN. METHODS Inpatients:1 From Chinese Traditional Medicine Hospital of Hubei Province.2 Conforming to the diagnostic standard of CGN.3 Conforming to mild,moderate and severe CGN.Scr≤442μ mol/L.4 Conforming to iusufficiency type of kidney-Yang and insufficiency type of kidney-Yin.5 The age from 18 to 65.Outpatients:1 The age under 18 or over 65,gestation or the women breastfeeding their childrenand allergic constitution.2 Induced by secondary factors.3 Amalgamating sever primary deseases.4 Scr>442μ mol/L.All 60 patients were randomly divided into two groups:control group(n=30), including 14 cases of iusufficiency type of kidney-Yang and 16 cases of insufficiency type of kidney-Yin ; therapeutic group(n=30),including 15 cases of insufficiency type of kidney-Yang and 15 cases of insufficiency type of kidney-Yin.There was no significant difference on age,sex,course,classify and cardinal symptoms distribution between two groups (p>0.05) .The control group was treated with routine medicine; The therapeutic group was not only treated with routine medicine but also taken Baoshen' gao point application four to six hours each time ,every ten days.The curative courses of both groups were three months.Observing the difference of both curative and safe indexes between before and behind treatments.All the data was deal with by stastistics of Spssll.5.Measurement data was adopted t-test,enumeration data was adoptd chi-squar test and grade data was adopted Ridit analysis. There was significant difference with P<0.05. And there was no significant difference withP>0.05.The standards of diagnosis and therapeutical effect were drew up according to"Guiding Principles for Clinical Study of New Chinese Medicines". RESULTS1 The total effective rate of the therapeutic group were 80%; while 53.3% on the control group. There was significant difference between two groups( p<0.05) ,which indicated that the therapeutic group had better effect than the control group.2 The effective rate of the therapeutic group to treat mild,moderate and severe...