Ridge Soup, Heat Strong Heat Treatment Of Blockage Ankylosing Spondylitis Of The Clinical Studies

The prevalence of ankylosing spondylitis (AS) is about 0.3% in China, and the number of the AS patients is over 4 million. The stiffness and pain of the spine and joints, which is caused by AS, seriously influence quality of the patients'life. However, the cause of AS is still unknown so far, so the therapy that can bring AS under complete control is not found. At the same time, the clinical Western medicine is less than satisfactory. Therefore, people are eager for a better therapy or medicine.My teacher, Professor Feng Xinghua who is a highly skilled and experienced person in the traditional Chinese medicine field has been engaged in treating rheumatism for many years. His Qingreqiangji Decoction is very effective and widely used in clinic. The purpose of my clinical research is to do further study on Qingreqiangji Decoction and define its efficacy and characteristics so as to recommend its clinical use.The cases, which were researched in this clinical study, come from Guang'an men Hospital, China Academy of Chinese Medical Sciences. The study compared the curative efficacy and safeness of Qingreqiangji Decoction with salicylazosulfapyridine (SASP). According to visiting sequence and following the principles of randomized controlled, this study chose 80 cases, and randomly divided them into two equal groups:Traditional Chinese medicine study group (group A, used Qingreqiangji Decoction for 24 weeks) and control group (group B, used SASP for 24 weeks). This study compared the clinical efficacy in the two groups from two aspects:the traditional Chinese medical evaluation and western medical evaluation. Through the method of contrasting the integral of syndrome of Traditional Chinese Medicine, the study evaluated the overall efficacy. What's more, it compared the symptom scores of the spine and peripheral joints in order to get to know the efficacies. At the same time, The general evaluation criterion western medical study used was ASAS20 (be recommend by ASAS). And it also compared the efficacies of Qingreqiangji Decoction and SASP in the treatment of the spine and peripheral joints.Traditional Chinese medical Results:the overall efficacy:the total effective rate of group A was 87.5%, and that of group B was 60.0%. The symptom improvement of the spine:The pains and limitations of the neck, back score:the total effective rate of group A was 62.5%, and that of group B was 40.0%. The symptom improvement of the peripheral joints:tumor (swelling), the calor (heat) and dolor (pain) of the peripheral joints:the total effective rate of group A was 85.7%, and that of group B was 59.0%. The remission of acetabulum pain:the total effective rate of group A was 76.5%, and that of group B was 60.7%.Western medical Results:the percentage of patients of group A who fit requirements of ASAS20 was 87.5%, and that of group B was 67.5%. At the same time, the percentage of patients of group A who fit requirements of BASDAI50 was 82.5%, and that of group B was 60.0%. So the general efficacy of group A was better than that of group B. The evaluations of the spine:(1) The VAS scores of spinal pains and the score of spinal inflammation:the treatment of the goup B was effective, with that of the goup A better. (2) The spinal movable degree:the rotation of cervical vertebra:although both treatments were effective, the goup A was better; the distance between tragus and wall: the treatment of goup A was effective, but that of group B was not; the lateral curvature of lumbar:the treatment of goup A was effective, but that of group B was not; the proneness of lumbar:the treatment of goup A was as effective as that of group B. The evaluations of the peripheral joints:(1) the VAS score of joint:both treatments were effective, but the goup A was better. (2)the number of swelling joints:the treatment of goup A was as effective as that of group B. The evaluations of the acetabulum joint:(1) The VAS scores of acetabulum pains: the treatment of the goup B was effective, with that of the goup A better. (2)the distance between the two anklebones:both treatments were effective, but the goup A was better.In a word, the efficacy of Qingreqiangji Decoction was better than that of SASP in the treatment of the spine and peripheral joints. Moreover, Qingreqiangji Decoction did well in the remission of acetabulum pain and the improvement of acetabulum joint activity.Neither adverse reactions nor abnormal assays were found in this clinical study. It is worth notice that there was no adverse reactions in the control group which should be common during using salicylazosulfapyridine (SASP), such as nausea, vomiting, and so on. It might be related to that the number of cases was so small.