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The Effect Of VE Supplement And Mimic Altitude Training On Antioxidant And Some Enzyme Of Energy Metabolism In SD Rats

Posted on:2004-09-10Degree:MasterType:Thesis
Country:ChinaCandidate:W P LiFull Text:PDF
GTID:2167360092987845Subject:Human Movement Science
Abstract/Summary:PDF Full Text Request
With the development of the altitude training, these terms, such as the altitude stress, living high - training low, mimic altitude training have become popular topic within athletes, coaches and researchers. According to a large quantity of present research data in this area, we can see that people focus their attention on the means and environment of altitude training, however, they seldom pay close attention to the attitude nutrition.The main difference between the high-altitude environment and the low-altitude environment is the lack of oxygen, which exerts great influence on all systems and metabolizability of organism. The biggest problem of altitude training will face with is how to fight the lack of oxygen. Vitamin E is one of the important antioxidant substances in the body, which can improve the physiologic function and the material metabolism. Vitamin E will also be helpful to enhance aerobic staying - power and the training level in the altitude training, therefore athletes can take some VE to resist the lack of oxygen when they are training on plateau.The research' s purpose is to confer the effects of mimic altitude training and the VE supplement in SD rats. The research tested the following index: the activity of superoxide dismutase (SOD), malondiadehyde (MDA), the aerobic enzyme MDH activity of skeletal muscles and the anaerobic enzyme LDH activity of skeletal muscles. The research object is SD rats which have been divided six group: plain contrast (A group), plain training (B group), altitude contrast (C group), altitude training (D group), altitude 5 times VE supplied (E group), altitude training and 5 times VE supplied (F group).Result of this study shows:1. The activity of body SOD is significantly higher than plain control (A group) and plain training (B group) after four weeks altitude training (p<0.01), the concentration of MDA is significantly lower than plain control (A group) and plain training(B group) (p<0. 01), which shows the advance of exercise capacity in the course of altitude training lies in the advancement of SOD and reduce of MDA.2. There is no significant change in the anaerobic enzyme LDH activity of skeletal muscles in plain contrast (A group) and plain training (B group) after four weeks altitude training , but compared with the contrast group, the aerobic enzyme MDH activity of skeletal muscles is increasedsignificantly (p<0. 01), which show: altitude training is very helpful to increase the activity of oxygen aerobic enzyme, but little effect to anaerobic metabolize enzyme.3. The reaction of oxidation of lipid in the condition of altitude will be increased , but after four weeks' high supplement of VE, the concentration of SOD is increased significantly, but MDA concentration in the blood serum is fallen (p<0. 01), these indicts: VE supplement can depress the reaction of lipid peroxidation (LPO) in the altitude environment.4. Under double effect of four weeks' supplement of VE and altitude training, the level of SOD is increased by 8.68% compared with only altitude training (p<0.01), but the level of MDA is decreased by 50.18% (p<0.01), which shows: the antioxidant capacity could be increased significantly thanks to the supplement of VE during altitude training.Therefore, we can draw the conclusion: during the altitude training there exists the good result that may be beneficial to the capacity of elimination of free radical or less production of free radical, and eliminating fatigue, recovering the energy if the antioxidant substance such as VE is supplied, and this also enhances the training level and antioxidant effect.
Keywords/Search Tags:altitude training, VE supplement, antioxidant, free radical, skeletal muscles, aerobic enzyme, anaerobic enzyme
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