Objective: To investigate the prevalence rate of depression in diabetic population and the relation between glucose metabolism and depression, to study the effect of comprehensive psychological intervention for patients with type 2 diabetes. Methods: In the first phase, seventy-one type 2 diabetes and ninety-seven healthy controls were assessed with Self-reporting Depression Scale (SDS), then seventy-one type 2 diabetes were interviewed and analyzed by Medical Coping Modes Questionnaire, (MCMQ) and Social Support Measure Scale. In the second phase, the patients were randomized to psychological intervening group or control group. The control group (n=32) was treated with conventional therapies. The psychological intervening group (n=33) received comprehensive psychological intervention in addition to conventional therapies. All patients were assessed by Self-reporting Depression Scale (SDS),Weight, serum fasting blood glucose(FBG) and post-prandial two hours blood glucose level(2PBG) were measured before the treatment and at the second ,third ,fifth month after treatment. Results: (l)The ratio of depression was higher in subjects with type 2 diabetes than in healthycontrols.(2)Depression was found to be positive correlated with sevenfactors in type 2 diabetic patients, which were woman, course, BMI, lower education level, diabetic complications, FBG, 2PBG and be negative correlated with social support ,facing.(3)A11 patients were demonstrated significant improvement in FBG, 2PBG and depressive symptoms after treatment, but the degree of improvement was significantly greater in the experimental group.(4)FBG, 2PBG and depressive symptoms were going up during follow-up. Conclusions: The prevalence rate of depression in diabetic patients is high, Comprehensive psychological intervention can improve clinical outcome, the depression of patients with type 2 diabetes. |