Effect Of Self-control Exercise On Immunoglobulin And Serum Complement In Malignant Tumor Patients

Objective:To study the influence of self-controlled exercise in serum immunoglobulins IgA, IgG, IgM and serum C3, C4 in malignant tumor patients who are in rehabilitation.Methods:Choose 47 malignant tumor patients in rehabilitation (from new participants of Shanghai cancer club rehabilitation class) (male 21, female 26), who had finished the conventional malignant tumor treatment, after six months of self-control exercise for 5-7 days a week, 1.5-2 hours a day. After 3 and 6 months'exercise take their blood sampling respectively in quiet condition, use ELISA method to test the level of serum immunoglobulins IgA, IgG, IgM and serum C3, C4.Results:After 3 months'self-control exercise, malignant tumor patients'serum IgA, IgG, IgM, C3, C4 level compared with level before experiment have been reduced (P < 0.001), increased (P < 0.001), increased (P < 0.001), reduced (P < 0.05), increased (P < 0.05) respectively. After 6 months'Self-control exercise the serum IgA level have changed with significant difference (P < 0.001) compared with before experimental, level of serum IgG compared with before experiment is still significantly higher (P < 0.001), After 6 months'self-control exercise,level of serum IgM is reduced down to the level before experiment, and compared with after 3 months'self-control exercise obviously decreased (P < 0.001), level of serum C3 increased, but still below the former level ;level of serum C4 goes down significantly (P < 0.05) compared with after 3 month's self-control exercise, but did not catch the level before experiment.Conclusion:A six-month self-control exercise can significantly improve the recovery period malignant tumor patient serum IgG level, reduce the malignant tumor patient serum IgA level, self-control exercise can improve the malignant tumor patient humoral immune function; Self-control exercise can control exercise have certain effect for malignant tumor patient on serum C3, C4 level. There is some difference between alimentary system cancer patients with other types of cancer patients humoral immune level between in each stage of self-control exercise.