The Therapeutic Courses Research Of Chronic Anal Eczema

Objective:By non-blinded randomized controlled study of chronic anal eczema treatment and treatment of disease, not only for clinical provide an effective and safe, easy, and difficult to relapse treatment.Methods:Clinical randomly selected 91 patients with chronic eczema anus, were randomly divided into control group 1, control group 2, treatment group, Compound Ku Shen Tang with smoked the first of about 20～25 minutes after the wash, dry amount after topical Xiong Zhen Ointment (hospital preparation), Compound Econazole Nitrate Cream, sooner or later the paint once every two weeks, local Fumigation, medication week, a week after drug withdrawal for two weeks. Control group 1, control group 2, treatment group, three groups of treatment was 2 months,4 months,6 months. After the end of treatment, observation of the following indicators: 1, Clinical efficacy of three groups; 2,The rate of major clinical symptoms disappeared; 3, Three groups after treatment, improvement of symptoms and signs points; 4, Months after treatment follow-up recurrence rates were observed.Results:1, Control group 1, control group 2, treatment group, the total effective rate was 68.75%,77.42% and 96.43%, by chi-square test, the treatment group and control group 1, control group comparison P values were 2=0.013.0.006, P<0.05, the three groups after treatment, significant difference between the total effective rate, the total effective rate in treatment group than the control group 1, control group 2. 2, Mainly on the rate of clinical symptoms, the chi-square test showed that the treatment group in the control group 1, pruritus, wet, skin lesions of three symptoms, control group 2 lesions of P=0.000. 3, The treatment group and control group 2, total score and the itching, wet, skin lesions and performance scores compared with the control group 1, P<0.05, statistically significant differences between treatment group and control group 2 than in control group 1. 4,The treatment group and control group 2, total score and the performance scores compared lesions, P<0.05, significantly different. However, after treatment, moisture, itching score of P> 0.05, no significant difference. 5, Three groups of patients relapse after 6 months follow-up compared to the situation: .control group 1 recurrence in 15 cases,9 cases of recurrence of the control group 2, treatment group,1 case of recurrence. X2=14.112, P=0.001, the treatment group with the control group 2, control group 1 were carried out chi-square test, p values were 0.009,0.000<0.05, the difference was statistically significant.Conclusion:Compound Ku Shen Tang, Xiong Zhen Ointment and Compound Econazole Nitrafe Cream Periodic topical treatment of chronic anal eczema for 6 months with a high cure rate, recurrence rate, the advantages of fewer side effects, is an effective and safe, easy, easy treatment of relapse.