Clinical Research Of Wenjing Tang On Female Insomnia Belonging To Type Of Jueyin Cold Obstruction And Blood Stasis

ObjectivesDiscussed the clinical effect of Wenjing Tang on female insomnia belonging to type of jueyin cold obstruction and blood stasis, in order to provide theoretical support and scientific basis for its further clinical applications and development.Methods30 female volunteers were diagnosed as insomnia belonging to type of jueyin cold obstruction and blood stasis from the outpatient of Guangdong Provincial Hospital from July 2010 to December 2010. Intervention programs:Chinese herbal drug(Wenjing Tang). Course of treatment:4 weeks. Before and after treatment and different time points during treatment were observerd by subjective assessment of sleep quality:Pittsburgh Sleep Quality Index questionnaire (PSQI) and Insomnia Severity Index Scale (ISI), emotional status assessement:Self-rating Anxiety Scale (SAS) and self-rating Depression Scale (SDS), assessment of life quality:the amount the World Health Organization Quality of Life Form (WHOQOL-BREF), and Subjective overall efficacy scoreResult1. Subjective sleep quality (1) Lowered dichotomy of PSQI scores:After treatment,22 cases got partial remission, accounting for 73.3%.(2)Lowered quadruplicity of PSQI scores:After treatment,8 cases got no remission, accounting for 34.6%.19 cases got partial remission, accounting for 34.6%,3 cases got markedly remission, accounting for 25%.(3) Factor scores and the total score of PSQI:After treatment, all factor scores of sleep quality, sleep latency, sleep time, sleep efficiency, sleep disturbance, sleep medication, daytime function and total score of PSQI decreased significantly (P<0.05) after treatment.(4) ISI:Total score of ISI in the 8th day, the 15th day, the 22th day, the 29th day decreased significantly compared with baseline (P<0.05). Total score of ISI in the 29th day decreased significantly compared with the 8th day(P <0.05). Total score of ISI in the 29th day decreased significantly compared with the 22th day (P<0.05).2. Emotional StatusTotal score of SAS decreased significantly after treatment (P< 0.05). Total score of SDS decreased after treatment. But the difference is not significant (P>0.05).3. Quality of lifeScore of physical areas and total score of Quality of life in the 29th day increased significantly compared with baseline(P<0.05).4. Subjective efficacy scoreThe score of subjective efficacy was 42.83±27.97 in the 8th day,49.67±24.00 in the 15th day,51.50±22.02 in the 22th day, and 58.26±18.58 in the 29th day. The difference between them were statistically significant (P<0.05)Conclusion1. Subjective sleep quality on female who are diagnosed insomnia belonging to type of jueyin cold obstruction and blood stasis can be effectively improved by Wenjing Tang. Sleep latency is shortened. Sleep time is extended. Sleep efficiency is improved. The clinical effect is fast and comprehensive.2.Wenjing Tang can effectively relieve patients'anxiety and depression in the study, especially for anxiety.3. Wenjing Tang can improve quality of life by improving physical condition.4. Factors of age and induced abortion are closely related with the occurrence of insomnia.